ProfileGDS5420 / 204116_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 64% 72% 65% 70% 72% 58% 50% 68% 56% 75% 70% 63% 63% 68% 65% 72% 68% 63% 58% 72% 65% 74% 69% 62% 56% 67% 64% 68% 58% 73% 58% 55% 77% 69% 63% 77% 70% 55% 61% 63% 75% 63% 45% 67% 66% 59% 65% 70% 60% 66% 59% 75% 74% 63% 70% 73% 52% 65% 70% 75% 68% 58% 63% 50% 69% 66% 62% 62% 75% 60% 67% 61% 76% 66% 64% 72% 66% 45% 62% 66% 44% 51% 59% 51% 62% 59% 38% 55% 60% 53% 63% 53% 59% 74% 59% 66% 59% 37% 59% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose419.2364
GSM1296119B_lesional_pre-dose645.3172
GSM1296076C_lesional_pre-dose396.5265
GSM1296092D_lesional_pre-dose565.5470
GSM1296103E_lesional_pre-dose669.4172
GSM1296078F_lesional_pre-dose252.0558
GSM1296107G_lesional_pre-dose181.5750
GSM1296109H_lesional_pre-dose522.6768
GSM1296080I_lesional_pre-dose242.9756
GSM1296090J_lesional_pre-dose780.6575
GSM1296074K_lesional_pre-dose534.9770
GSM1296111L_lesional_pre-dose392.2563
GSM1296099M_lesional_pre-dose382.8163
GSM1296086O_lesional_pre-dose508.5968
GSM1296117P_lesional_pre-dose439.6265
GSM1296113Q_lesional_pre-dose657.1472
GSM1296096R_lesional_pre-dose523.6268
GSM1296105S_lesional_pre-dose399.0463
GSM1296098T_lesional_pre-dose289.8158
GSM1296101U_lesional_pre-dose657.4772
GSM1296121V_lesional_pre-dose429.165
GSM1296088W_lesional_pre-dose742.6974
GSM1296082X_lesional_pre-dose530.9369
GSM1296115Y_lesional_pre-dose367.5562
GSM1296084Z_lesional_pre-dose243.2656
GSM1296072B_lesional_day8479.2267
GSM1296069L_lesional_day8424.0564
GSM1296071P_lesional_day8533.2768
GSM1296070Y_lesional_day8299.9258
GSM1296073V_lesional_day8670.6373
GSM1296034A_lesional_day15299.3158
GSM1296041G_lesional_day15240.6155
GSM1296035R_lesional_day15893.5677
GSM1296038U_lesional_day15541.4669
GSM1296047B_lesional_day15385.7963
GSM1296039E_lesional_day15846.3277
GSM1296042H_lesional_day15590.7470
GSM1296043L_lesional_day15262.7455
GSM1296037M_lesional_day15352.4161
GSM1296046P_lesional_day15392.8763
GSM1296044Q_lesional_day15766.975
GSM1296045Y_lesional_day15383.7263
GSM1296025C_lesional_day15125.0345
GSM1296033D_lesional_day15497.667
GSM1296027I_lesional_day15453.1266
GSM1296032J_lesional_day15316.5859
GSM1296024K_lesional_day15425.4965
GSM1296031W_lesional_day15578.7470
GSM1296028X_lesional_day15312.560
GSM1296029Z_lesional_day15466.1666
GSM1296026F_lesional_day15282.4759
GSM1296030O_lesional_day15773.7975
GSM1296040S_lesional_day15743.9174
GSM1296036T_lesional_day15406.4563
GSM1296048V_lesional_day15564.1270
GSM1296059A_lesional_day43674.7473
GSM1296066G_lesional_day43209.2152
GSM1296060R_lesional_day43425.1465
GSM1296063U_lesional_day43578.9970
GSM1296064E_lesional_day43749.1275
GSM1296067H_lesional_day43527.7768
GSM1296062M_lesional_day43292.3558
GSM1296068Q_lesional_day43402.9663
GSM1296050C_lesional_day43168.5750
GSM1296057D_lesional_day43535.3269
GSM1296052I_lesional_day43435.5466
GSM1296054J_lesional_day43373.8462
GSM1296049K_lesional_day43345.1862
GSM1296055W_lesional_day43766.6775
GSM1296053X_lesional_day43320.2760
GSM1296058Z_lesional_day43493.467
GSM1296051F_lesional_day43309.8761
GSM1296056O_lesional_day43804.9676
GSM1296065S_lesional_day43450.3366
GSM1296061T_lesional_day43415.5364
GSM1296095A_non-lesional_pre-dose624.8972
GSM1296120B_non-lesional_pre-dose463.466
GSM1296077C_non-lesional_pre-dose122.6845
GSM1296093D_non-lesional_pre-dose382.1862
GSM1296104E_non-lesional_pre-dose447.8466
GSM1296079F_non-lesional_pre-dose111.844
GSM1296108G_non-lesional_pre-dose196.5551
GSM1296110H_non-lesional_pre-dose323.0259
GSM1296081I_non-lesional_pre-dose172.251
GSM1296091J_non-lesional_pre-dose359.6362
GSM1296075K_non-lesional_pre-dose283.6459
GSM1296112L_non-lesional_pre-dose102.8238
GSM1296100M_non-lesional_pre-dose239.7955
GSM1296087O_non-lesional_pre-dose291.5460
GSM1296118P_non-lesional_pre-dose231.0553
GSM1296114Q_non-lesional_pre-dose393.7863
GSM1296097R_non-lesional_pre-dose204.2653
GSM1296106S_non-lesional_pre-dose313.3659
GSM1296102U_non-lesional_pre-dose734.5674
GSM1296122V_non-lesional_pre-dose303.9759
GSM1296089W_non-lesional_pre-dose455.0766
GSM1296083X_non-lesional_pre-dose308.5459
GSM1296116Y_non-lesional_pre-dose96.4337
GSM1296085Z_non-lesional_pre-dose294.1259