ProfileGDS5420 / 203746_s_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 71% 70% 66% 71% 81% 72% 64% 69% 59% 70% 71% 69% 75% 73% 67% 58% 77% 60% 67% 67% 68% 65% 74% 74% 63% 58% 65% 61% 65% 73% 47% 65% 73% 68% 61% 76% 65% 64% 63% 58% 58% 57% 51% 57% 60% 53% 46% 62% 53% 57% 62% 68% 71% 57% 70% 75% 64% 71% 69% 78% 59% 68% 56% 51% 66% 51% 45% 50% 70% 48% 73% 69% 77% 66% 56% 71% 61% 53% 50% 73% 52% 58% 52% 50% 61% 57% 59% 69% 59% 56% 56% 73% 58% 58% 62% 58% 57% 58% 54% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose627.371
GSM1296119B_lesional_pre-dose565.9670
GSM1296076C_lesional_pre-dose411.9166
GSM1296092D_lesional_pre-dose606.8171
GSM1296103E_lesional_pre-dose1102.281
GSM1296078F_lesional_pre-dose631.9572
GSM1296107G_lesional_pre-dose409.9964
GSM1296109H_lesional_pre-dose557.6469
GSM1296080I_lesional_pre-dose285.159
GSM1296090J_lesional_pre-dose556.870
GSM1296074K_lesional_pre-dose596.5271
GSM1296111L_lesional_pre-dose551.3469
GSM1296099M_lesional_pre-dose763.3275
GSM1296086O_lesional_pre-dose693.9173
GSM1296117P_lesional_pre-dose498.0367
GSM1296113Q_lesional_pre-dose299.3758
GSM1296096R_lesional_pre-dose903.9877
GSM1296105S_lesional_pre-dose322.9160
GSM1296098T_lesional_pre-dose480.9367
GSM1296101U_lesional_pre-dose481.6467
GSM1296121V_lesional_pre-dose504.0368
GSM1296088W_lesional_pre-dose416.3565
GSM1296082X_lesional_pre-dose705.9774
GSM1296115Y_lesional_pre-dose708.5774
GSM1296084Z_lesional_pre-dose37263
GSM1296072B_lesional_day8297.6158
GSM1296069L_lesional_day8438.1365
GSM1296071P_lesional_day8352.2161
GSM1296070Y_lesional_day8433.2665
GSM1296073V_lesional_day8682.373
GSM1296034A_lesional_day15151.3947
GSM1296041G_lesional_day15419.0465
GSM1296035R_lesional_day15691.173
GSM1296038U_lesional_day15520.4768
GSM1296047B_lesional_day15343.7561
GSM1296039E_lesional_day15818.176
GSM1296042H_lesional_day15428.765
GSM1296043L_lesional_day15416.9364
GSM1296037M_lesional_day15379.5663
GSM1296046P_lesional_day15302.2658
GSM1296044Q_lesional_day15303.0358
GSM1296045Y_lesional_day15287.5557
GSM1296025C_lesional_day15173.7351
GSM1296033D_lesional_day15272.3257
GSM1296027I_lesional_day15300.2960
GSM1296032J_lesional_day15207.3853
GSM1296024K_lesional_day15127.4246
GSM1296031W_lesional_day15361.662
GSM1296028X_lesional_day15208.8253
GSM1296029Z_lesional_day15261.157
GSM1296026F_lesional_day15342.0262
GSM1296030O_lesional_day15508.0968
GSM1296040S_lesional_day15610.9871
GSM1296036T_lesional_day15280.7457
GSM1296048V_lesional_day15582.7770
GSM1296059A_lesional_day43785.8475
GSM1296066G_lesional_day43404.9764
GSM1296060R_lesional_day43613.3971
GSM1296063U_lesional_day43544.569
GSM1296064E_lesional_day43904.7378
GSM1296067H_lesional_day43327.6459
GSM1296062M_lesional_day43537.3968
GSM1296068Q_lesional_day43282.2956
GSM1296050C_lesional_day43181.5251
GSM1296057D_lesional_day43450.9166
GSM1296052I_lesional_day43172.2351
GSM1296054J_lesional_day43128.8545
GSM1296049K_lesional_day43164.5250
GSM1296055W_lesional_day43599.3170
GSM1296053X_lesional_day43157.0448
GSM1296058Z_lesional_day43717.0973
GSM1296051F_lesional_day43517.969
GSM1296056O_lesional_day43854.3877
GSM1296065S_lesional_day43445.9666
GSM1296061T_lesional_day43254.7956
GSM1296095A_non-lesional_pre-dose607.0771
GSM1296120B_non-lesional_pre-dose339.0561
GSM1296077C_non-lesional_pre-dose193.3553
GSM1296093D_non-lesional_pre-dose186.7850
GSM1296104E_non-lesional_pre-dose684.3573
GSM1296079F_non-lesional_pre-dose192.4252
GSM1296108G_non-lesional_pre-dose292.8158
GSM1296110H_non-lesional_pre-dose215.0852
GSM1296081I_non-lesional_pre-dose157.6350
GSM1296091J_non-lesional_pre-dose319.7161
GSM1296075K_non-lesional_pre-dose251.0257
GSM1296112L_non-lesional_pre-dose327.159
GSM1296100M_non-lesional_pre-dose568.9769
GSM1296087O_non-lesional_pre-dose285.4359
GSM1296118P_non-lesional_pre-dose266.2156
GSM1296114Q_non-lesional_pre-dose271.4956
GSM1296097R_non-lesional_pre-dose665.3573
GSM1296106S_non-lesional_pre-dose298.7358
GSM1296102U_non-lesional_pre-dose308.3658
GSM1296122V_non-lesional_pre-dose368.5662
GSM1296089W_non-lesional_pre-dose296.3358
GSM1296083X_non-lesional_pre-dose267.7657
GSM1296116Y_non-lesional_pre-dose299.2558
GSM1296085Z_non-lesional_pre-dose215.754