ProfileGDS5420 / 202623_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 90% 95% 93% 92% 86% 94% 95% 92% 89% 91% 93% 95% 91% 89% 96% 94% 90% 90% 86% 89% 94% 89% 93% 95% 88% 95% 95% 95% 95% 94% 81% 96% 91% 90% 94% 92% 95% 95% 87% 96% 95% 95% 91% 91% 89% 89% 91% 87% 91% 86% 93% 87% 86% 85% 94% 84% 96% 92% 90% 91% 94% 84% 94% 93% 90% 86% 85% 93% 91% 86% 88% 93% 91% 93% 86% 93% 94% 93% 88% 90% 93% 95% 94% 86% 90% 93% 95% 85% 89% 95% 95% 91% 93% 88% 93% 88% 84% 95% 87% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose2131.2490
GSM1296119B_lesional_pre-dose3298.8695
GSM1296076C_lesional_pre-dose3253.4993
GSM1296092D_lesional_pre-dose2724.9392
GSM1296103E_lesional_pre-dose1561.5286
GSM1296078F_lesional_pre-dose3512.5594
GSM1296107G_lesional_pre-dose3776.9895
GSM1296109H_lesional_pre-dose2503.5692
GSM1296080I_lesional_pre-dose2010.6789
GSM1296090J_lesional_pre-dose2549.1991
GSM1296074K_lesional_pre-dose3239.7893
GSM1296111L_lesional_pre-dose3455.0995
GSM1296099M_lesional_pre-dose2292.1391
GSM1296086O_lesional_pre-dose2162.4389
GSM1296117P_lesional_pre-dose3655.8496
GSM1296113Q_lesional_pre-dose3010.6694
GSM1296096R_lesional_pre-dose2184.1590
GSM1296105S_lesional_pre-dose2094.9790
GSM1296098T_lesional_pre-dose1593.5486
GSM1296101U_lesional_pre-dose2038.789
GSM1296121V_lesional_pre-dose3268.2194
GSM1296088W_lesional_pre-dose1998.9389
GSM1296082X_lesional_pre-dose3010.0293
GSM1296115Y_lesional_pre-dose3456.8995
GSM1296084Z_lesional_pre-dose1841.2988
GSM1296072B_lesional_day83205.8895
GSM1296069L_lesional_day83270.4495
GSM1296071P_lesional_day83086.3895
GSM1296070Y_lesional_day8324495
GSM1296073V_lesional_day83303.5794
GSM1296034A_lesional_day151116.8281
GSM1296041G_lesional_day154019.6196
GSM1296035R_lesional_day152289.0191
GSM1296038U_lesional_day152136.990
GSM1296047B_lesional_day152984.6194
GSM1296039E_lesional_day152694.5692
GSM1296042H_lesional_day153500.6995
GSM1296043L_lesional_day153165.9195
GSM1296037M_lesional_day151673.0387
GSM1296046P_lesional_day153295.2696
GSM1296044Q_lesional_day152998.8495
GSM1296045Y_lesional_day153255.4695
GSM1296025C_lesional_day152289.7291
GSM1296033D_lesional_day152253.7191
GSM1296027I_lesional_day152148.7389
GSM1296032J_lesional_day151918.5789
GSM1296024K_lesional_day152309.8691
GSM1296031W_lesional_day151647.7887
GSM1296028X_lesional_day152243.4691
GSM1296029Z_lesional_day151597.6386
GSM1296026F_lesional_day153030.6593
GSM1296030O_lesional_day151773.9987
GSM1296040S_lesional_day151582.0886
GSM1296036T_lesional_day151398.2985
GSM1296048V_lesional_day153052.1994
GSM1296059A_lesional_day431398.3884
GSM1296066G_lesional_day433806.1996
GSM1296060R_lesional_day432557.8392
GSM1296063U_lesional_day432241.590
GSM1296064E_lesional_day432483.1491
GSM1296067H_lesional_day432790.2394
GSM1296062M_lesional_day431379.9284
GSM1296068Q_lesional_day432828.594
GSM1296050C_lesional_day432963.7493
GSM1296057D_lesional_day432151.5790
GSM1296052I_lesional_day431652.5286
GSM1296054J_lesional_day431468.2485
GSM1296049K_lesional_day432810.8993
GSM1296055W_lesional_day432363.5591
GSM1296053X_lesional_day431516.8386
GSM1296058Z_lesional_day431865.9388
GSM1296051F_lesional_day432959.4993
GSM1296056O_lesional_day432395.9891
GSM1296065S_lesional_day432600.6593
GSM1296061T_lesional_day431534.3486
GSM1296095A_non-lesional_pre-dose2992.8993
GSM1296120B_non-lesional_pre-dose3073.7394
GSM1296077C_non-lesional_pre-dose2825.8893
GSM1296093D_non-lesional_pre-dose1739.7288
GSM1296104E_non-lesional_pre-dose2323.8590
GSM1296079F_non-lesional_pre-dose2851.7393
GSM1296108G_non-lesional_pre-dose3690.1795
GSM1296110H_non-lesional_pre-dose2861.5494
GSM1296081I_non-lesional_pre-dose1652.9786
GSM1296091J_non-lesional_pre-dose2171.1690
GSM1296075K_non-lesional_pre-dose3007.1893
GSM1296112L_non-lesional_pre-dose2907.9895
GSM1296100M_non-lesional_pre-dose1484.0385
GSM1296087O_non-lesional_pre-dose2149.9689
GSM1296118P_non-lesional_pre-dose3079.7695
GSM1296114Q_non-lesional_pre-dose3241.9695
GSM1296097R_non-lesional_pre-dose2395.0391
GSM1296106S_non-lesional_pre-dose2532.1693
GSM1296102U_non-lesional_pre-dose1723.2588
GSM1296122V_non-lesional_pre-dose2659.4993
GSM1296089W_non-lesional_pre-dose1818.4488
GSM1296083X_non-lesional_pre-dose1400.7784
GSM1296116Y_non-lesional_pre-dose3197.7595
GSM1296085Z_non-lesional_pre-dose1682.2987