ProfileGDS5420 / 201882_x_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 69% 63% 63% 63% 54% 66% 67% 60% 56% 55% 60% 65% 62% 62% 66% 62% 68% 54% 69% 68% 62% 57% 61% 70% 63% 61% 69% 53% 54% 61% 67% 69% 63% 69% 59% 55% 54% 65% 64% 64% 64% 60% 55% 49% 50% 63% 56% 62% 47% 58% 66% 57% 61% 60% 63% 71% 68% 72% 65% 60% 60% 59% 59% 72% 61% 54% 51% 59% 56% 49% 68% 60% 54% 65% 55% 61% 56% 65% 55% 52% 61% 70% 53% 52% 53% 64% 54% 76% 59% 60% 66% 59% 65% 45% 69% 63% 50% 63% 57% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose565.3469
GSM1296119B_lesional_pre-dose387.5763
GSM1296076C_lesional_pre-dose354.0463
GSM1296092D_lesional_pre-dose354.1263
GSM1296103E_lesional_pre-dose222.6654
GSM1296078F_lesional_pre-dose424.6466
GSM1296107G_lesional_pre-dose466.5167
GSM1296109H_lesional_pre-dose325.8560
GSM1296080I_lesional_pre-dose234.3256
GSM1296090J_lesional_pre-dose224.7155
GSM1296074K_lesional_pre-dose290.3160
GSM1296111L_lesional_pre-dose438.1665
GSM1296099M_lesional_pre-dose368.3362
GSM1296086O_lesional_pre-dose341.7862
GSM1296117P_lesional_pre-dose448.0566
GSM1296113Q_lesional_pre-dose372.462
GSM1296096R_lesional_pre-dose512.4968
GSM1296105S_lesional_pre-dose237.454
GSM1296098T_lesional_pre-dose552.1569
GSM1296101U_lesional_pre-dose531.6868
GSM1296121V_lesional_pre-dose351.6962
GSM1296088W_lesional_pre-dose260.7857
GSM1296082X_lesional_pre-dose319.3961
GSM1296115Y_lesional_pre-dose557.8270
GSM1296084Z_lesional_pre-dose372.1563
GSM1296072B_lesional_day8348.4761
GSM1296069L_lesional_day8561.0969
GSM1296071P_lesional_day8237.5753
GSM1296070Y_lesional_day8243.8154
GSM1296073V_lesional_day8321.561
GSM1296034A_lesional_day15512.5167
GSM1296041G_lesional_day15525.1769
GSM1296035R_lesional_day15379.163
GSM1296038U_lesional_day15540.3669
GSM1296047B_lesional_day15317.9259
GSM1296039E_lesional_day15231.1855
GSM1296042H_lesional_day15235.3954
GSM1296043L_lesional_day15452.765
GSM1296037M_lesional_day15422.4764
GSM1296046P_lesional_day15414.1364
GSM1296044Q_lesional_day1542964
GSM1296045Y_lesional_day15340.8860
GSM1296025C_lesional_day15228.955
GSM1296033D_lesional_day15164.749
GSM1296027I_lesional_day15157.8550
GSM1296032J_lesional_day15388.163
GSM1296024K_lesional_day15238.2456
GSM1296031W_lesional_day15380.9762
GSM1296028X_lesional_day15140.947
GSM1296029Z_lesional_day15289.4158
GSM1296026F_lesional_day15438.2766
GSM1296030O_lesional_day15241.2257
GSM1296040S_lesional_day15348.1561
GSM1296036T_lesional_day15329.0160
GSM1296048V_lesional_day15380.1963
GSM1296059A_lesional_day43614.771
GSM1296066G_lesional_day43517.3268
GSM1296060R_lesional_day43648.5772
GSM1296063U_lesional_day43420.4165
GSM1296064E_lesional_day43315.6160
GSM1296067H_lesional_day43343.2960
GSM1296062M_lesional_day43307.9759
GSM1296068Q_lesional_day43318.2859
GSM1296050C_lesional_day43651.9372
GSM1296057D_lesional_day43351.9961
GSM1296052I_lesional_day43206.2154
GSM1296054J_lesional_day43189.7451
GSM1296049K_lesional_day43300.1359
GSM1296055W_lesional_day43253.7656
GSM1296053X_lesional_day43162.6149
GSM1296058Z_lesional_day43527.9768
GSM1296051F_lesional_day43303.8760
GSM1296056O_lesional_day43213.6454
GSM1296065S_lesional_day43427.165
GSM1296061T_lesional_day43244.4255
GSM1296095A_non-lesional_pre-dose338.2261
GSM1296120B_non-lesional_pre-dose268.5256
GSM1296077C_non-lesional_pre-dose406.2165
GSM1296093D_non-lesional_pre-dose242.5555
GSM1296104E_non-lesional_pre-dose199.4152
GSM1296079F_non-lesional_pre-dose322.5361
GSM1296108G_non-lesional_pre-dose572.8370
GSM1296110H_non-lesional_pre-dose237.9153
GSM1296081I_non-lesional_pre-dose182.0652
GSM1296091J_non-lesional_pre-dose199.6853
GSM1296075K_non-lesional_pre-dose376.8564
GSM1296112L_non-lesional_pre-dose253.6854
GSM1296100M_non-lesional_pre-dose815.4576
GSM1296087O_non-lesional_pre-dose276.759
GSM1296118P_non-lesional_pre-dose337.9860
GSM1296114Q_non-lesional_pre-dose471.2866
GSM1296097R_non-lesional_pre-dose299.1659
GSM1296106S_non-lesional_pre-dose452.8665
GSM1296102U_non-lesional_pre-dose134.1545
GSM1296122V_non-lesional_pre-dose528.9969
GSM1296089W_non-lesional_pre-dose404.2463
GSM1296083X_non-lesional_pre-dose176.8150
GSM1296116Y_non-lesional_pre-dose395.9363
GSM1296085Z_non-lesional_pre-dose269.9957