ProfileGDS5420 / 201717_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 86% 93% 92% 93% 86% 91% 92% 84% 83% 93% 91% 91% 92% 92% 92% 92% 90% 85% 85% 91% 92% 89% 94% 94% 91% 93% 89% 90% 93% 93% 77% 93% 92% 92% 91% 94% 91% 90% 89% 92% 91% 92% 78% 90% 84% 90% 81% 88% 90% 87% 84% 89% 85% 83% 92% 88% 92% 92% 93% 94% 86% 87% 90% 86% 94% 86% 85% 80% 91% 85% 91% 89% 94% 92% 81% 94% 92% 83% 86% 95% 83% 91% 86% 83% 92% 88% 90% 93% 89% 90% 90% 92% 89% 88% 93% 90% 84% 90% 89% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose1550.4786
GSM1296119B_lesional_pre-dose2701.2893
GSM1296076C_lesional_pre-dose2922.8792
GSM1296092D_lesional_pre-dose3060.3893
GSM1296103E_lesional_pre-dose1633.0786
GSM1296078F_lesional_pre-dose2571.291
GSM1296107G_lesional_pre-dose2493.4892
GSM1296109H_lesional_pre-dose1309.4384
GSM1296080I_lesional_pre-dose1355.2883
GSM1296090J_lesional_pre-dose3108.693
GSM1296074K_lesional_pre-dose2517.8991
GSM1296111L_lesional_pre-dose2276.7491
GSM1296099M_lesional_pre-dose2396.8392
GSM1296086O_lesional_pre-dose2783.3292
GSM1296117P_lesional_pre-dose2575.3192
GSM1296113Q_lesional_pre-dose2402.2892
GSM1296096R_lesional_pre-dose2254.1290
GSM1296105S_lesional_pre-dose1460.2385
GSM1296098T_lesional_pre-dose1410.2785
GSM1296101U_lesional_pre-dose2372.2491
GSM1296121V_lesional_pre-dose2541.6592
GSM1296088W_lesional_pre-dose1984.4489
GSM1296082X_lesional_pre-dose3566.1294
GSM1296115Y_lesional_pre-dose2952.794
GSM1296084Z_lesional_pre-dose2272.4591
GSM1296072B_lesional_day82700.6293
GSM1296069L_lesional_day81825.1989
GSM1296071P_lesional_day82004.3490
GSM1296070Y_lesional_day82678.8293
GSM1296073V_lesional_day82880.1893
GSM1296034A_lesional_day15897.2177
GSM1296041G_lesional_day152974.2793
GSM1296035R_lesional_day152628.9892
GSM1296038U_lesional_day152632.2792
GSM1296047B_lesional_day152286.4291
GSM1296039E_lesional_day153701.894
GSM1296042H_lesional_day152322.2891
GSM1296043L_lesional_day152020.1590
GSM1296037M_lesional_day151965.989
GSM1296046P_lesional_day152423.0392
GSM1296044Q_lesional_day152165.1591
GSM1296045Y_lesional_day152353.4392
GSM1296025C_lesional_day15921.4278
GSM1296033D_lesional_day152030.8890
GSM1296027I_lesional_day151458.7884
GSM1296032J_lesional_day152051.1990
GSM1296024K_lesional_day151185.4581
GSM1296031W_lesional_day151724.6688
GSM1296028X_lesional_day152181.2990
GSM1296029Z_lesional_day151641.6487
GSM1296026F_lesional_day151367.9284
GSM1296030O_lesional_day152014.6489
GSM1296040S_lesional_day151464.8985
GSM1296036T_lesional_day151267.3583
GSM1296048V_lesional_day152627.492
GSM1296059A_lesional_day431904.2288
GSM1296066G_lesional_day432536.1892
GSM1296060R_lesional_day432443.9592
GSM1296063U_lesional_day432995.7993
GSM1296064E_lesional_day433607.6194
GSM1296067H_lesional_day431532.3386
GSM1296062M_lesional_day431706.6487
GSM1296068Q_lesional_day432041.790
GSM1296050C_lesional_day431624.8286
GSM1296057D_lesional_day432950.2794
GSM1296052I_lesional_day431609.5786
GSM1296054J_lesional_day431398.4585
GSM1296049K_lesional_day431065.2780
GSM1296055W_lesional_day432274.9491
GSM1296053X_lesional_day431434.2585
GSM1296058Z_lesional_day432401.1391
GSM1296051F_lesional_day432159.0289
GSM1296056O_lesional_day433283.8294
GSM1296065S_lesional_day432543.5992
GSM1296061T_lesional_day431140.7981
GSM1296095A_non-lesional_pre-dose3339.2494
GSM1296120B_non-lesional_pre-dose2494.8392
GSM1296077C_non-lesional_pre-dose1325.1883
GSM1296093D_non-lesional_pre-dose1537.886
GSM1296104E_non-lesional_pre-dose4073.495
GSM1296079F_non-lesional_pre-dose1321.2983
GSM1296108G_non-lesional_pre-dose2348.3791
GSM1296110H_non-lesional_pre-dose1535.186
GSM1296081I_non-lesional_pre-dose1293.0583
GSM1296091J_non-lesional_pre-dose2678.4492
GSM1296075K_non-lesional_pre-dose2005.3588
GSM1296112L_non-lesional_pre-dose1942.690
GSM1296100M_non-lesional_pre-dose2826.5993
GSM1296087O_non-lesional_pre-dose2066.9189
GSM1296118P_non-lesional_pre-dose2056.390
GSM1296114Q_non-lesional_pre-dose2051.0290
GSM1296097R_non-lesional_pre-dose2533.0692
GSM1296106S_non-lesional_pre-dose1958.3889
GSM1296102U_non-lesional_pre-dose1777.4688
GSM1296122V_non-lesional_pre-dose2845.9593
GSM1296089W_non-lesional_pre-dose1978.6490
GSM1296083X_non-lesional_pre-dose1383.7284
GSM1296116Y_non-lesional_pre-dose1925.6790
GSM1296085Z_non-lesional_pre-dose1910.9189