ProfileGDS5420 / 201606_s_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 71% 80% 68% 69% 77% 69% 81% 83% 60% 70% 68% 81% 74% 71% 83% 78% 75% 66% 71% 70% 81% 68% 72% 84% 68% 75% 80% 77% 78% 78% 69% 80% 71% 75% 76% 73% 78% 79% 63% 76% 77% 78% 59% 61% 52% 62% 58% 66% 62% 60% 53% 57% 72% 73% 77% 73% 80% 72% 74% 80% 77% 71% 77% 59% 67% 53% 61% 56% 71% 59% 63% 63% 72% 71% 71% 75% 78% 59% 60% 73% 59% 78% 79% 62% 66% 63% 80% 66% 55% 79% 76% 72% 69% 65% 76% 67% 61% 80% 60% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose609.6571
GSM1296119B_lesional_pre-dose1022.9380
GSM1296076C_lesional_pre-dose469.768
GSM1296092D_lesional_pre-dose542.4569
GSM1296103E_lesional_pre-dose895.3477
GSM1296078F_lesional_pre-dose514.5469
GSM1296107G_lesional_pre-dose1121.7781
GSM1296109H_lesional_pre-dose1253.0983
GSM1296080I_lesional_pre-dose304.4660
GSM1296090J_lesional_pre-dose551.1470
GSM1296074K_lesional_pre-dose466.9368
GSM1296111L_lesional_pre-dose1111.8481
GSM1296099M_lesional_pre-dose760.6474
GSM1296086O_lesional_pre-dose595.5571
GSM1296117P_lesional_pre-dose1216.883
GSM1296113Q_lesional_pre-dose931.5278
GSM1296096R_lesional_pre-dose779.7675
GSM1296105S_lesional_pre-dose462.1966
GSM1296098T_lesional_pre-dose618.8371
GSM1296101U_lesional_pre-dose574.4970
GSM1296121V_lesional_pre-dose1139.8681
GSM1296088W_lesional_pre-dose524.368
GSM1296082X_lesional_pre-dose640.5672
GSM1296115Y_lesional_pre-dose133384
GSM1296084Z_lesional_pre-dose519.9668
GSM1296072B_lesional_day8790.9875
GSM1296069L_lesional_day81005.9780
GSM1296071P_lesional_day8868.0377
GSM1296070Y_lesional_day8923.9978
GSM1296073V_lesional_day8943.9978
GSM1296034A_lesional_day15580.7769
GSM1296041G_lesional_day151074.680
GSM1296035R_lesional_day15611.7271
GSM1296038U_lesional_day15768.6275
GSM1296047B_lesional_day15841.9376
GSM1296039E_lesional_day15653.3673
GSM1296042H_lesional_day15902.1678
GSM1296043L_lesional_day15965.9279
GSM1296037M_lesional_day15391.8863
GSM1296046P_lesional_day15820.0576
GSM1296044Q_lesional_day15877.2877
GSM1296045Y_lesional_day15926.4478
GSM1296025C_lesional_day15292.2559
GSM1296033D_lesional_day15332.9161
GSM1296027I_lesional_day15178.0152
GSM1296032J_lesional_day15372.6862
GSM1296024K_lesional_day15274.4458
GSM1296031W_lesional_day15463.4466
GSM1296028X_lesional_day15364.7562
GSM1296029Z_lesional_day15328.3460
GSM1296026F_lesional_day15197.4553
GSM1296030O_lesional_day15245.8157
GSM1296040S_lesional_day15652.8372
GSM1296036T_lesional_day15708.9173
GSM1296048V_lesional_day15871.2877
GSM1296059A_lesional_day43677.9173
GSM1296066G_lesional_day431041.3880
GSM1296060R_lesional_day43676.3272
GSM1296063U_lesional_day43739.3974
GSM1296064E_lesional_day431034.4680
GSM1296067H_lesional_day43892.5977
GSM1296062M_lesional_day43614.1271
GSM1296068Q_lesional_day43865.4377
GSM1296050C_lesional_day43288.8459
GSM1296057D_lesional_day43490.3667
GSM1296052I_lesional_day43191.9953
GSM1296054J_lesional_day43353.8961
GSM1296049K_lesional_day43242.956
GSM1296055W_lesional_day43623.2671
GSM1296053X_lesional_day43296.8659
GSM1296058Z_lesional_day43372.9463
GSM1296051F_lesional_day43361.8863
GSM1296056O_lesional_day43620.4572
GSM1296065S_lesional_day43619.7171
GSM1296061T_lesional_day43626.7171
GSM1296095A_non-lesional_pre-dose784.4975
GSM1296120B_non-lesional_pre-dose907.1278
GSM1296077C_non-lesional_pre-dose299.3859
GSM1296093D_non-lesional_pre-dose329.3160
GSM1296104E_non-lesional_pre-dose665.8873
GSM1296079F_non-lesional_pre-dose283.5459
GSM1296108G_non-lesional_pre-dose949.8278
GSM1296110H_non-lesional_pre-dose959.3379
GSM1296081I_non-lesional_pre-dose357.762
GSM1296091J_non-lesional_pre-dose436.5666
GSM1296075K_non-lesional_pre-dose361.2263
GSM1296112L_non-lesional_pre-dose1028.5780
GSM1296100M_non-lesional_pre-dose470.2966
GSM1296087O_non-lesional_pre-dose210.6455
GSM1296118P_non-lesional_pre-dose974.1579
GSM1296114Q_non-lesional_pre-dose822.0276
GSM1296097R_non-lesional_pre-dose645.7972
GSM1296106S_non-lesional_pre-dose556.4269
GSM1296102U_non-lesional_pre-dose437.2665
GSM1296122V_non-lesional_pre-dose813.676
GSM1296089W_non-lesional_pre-dose488.5667
GSM1296083X_non-lesional_pre-dose337.5361
GSM1296116Y_non-lesional_pre-dose1012.980
GSM1296085Z_non-lesional_pre-dose325.9660