ProfileGDS5420 / 1568682_a_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 12% 19% 17% 24% 19% 24% 13% 14% 17% 17% 13% 22% 14% 22% 24% 24% 20% 6% 4% 11% 18% 19% 19% 22% 22% 12% 16% 15% 21% 21% 20% 23% 22% 1% 26% 35% 21% 13% 21% 21% 18% 17% 16% 20% 13% 17% 26% 12% 28% 6% 16% 8% 24% 24% 24% 2% 25% 22% 15% 10% 25% 17% 14% 19% 15% 21% 14% 25% 10% 25% 1% 29% 10% 2% 1% 18% 23% 11% 19% 12% 24% 8% 15% 15% 25% 18% 16% 10% 18% 22% 15% 20% 8% 20% 25% 12% 22% 17% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose12.212
GSM1296119B_lesional_pre-dose25.0819
GSM1296076C_lesional_pre-dose21.0517
GSM1296092D_lesional_pre-dose26.6524
GSM1296103E_lesional_pre-dose20.5219
GSM1296078F_lesional_pre-dose32.2724
GSM1296107G_lesional_pre-dose16.0213
GSM1296109H_lesional_pre-dose16.514
GSM1296080I_lesional_pre-dose16.917
GSM1296090J_lesional_pre-dose17.1617
GSM1296074K_lesional_pre-dose12.7613
GSM1296111L_lesional_pre-dose34.0622
GSM1296099M_lesional_pre-dose14.3914
GSM1296086O_lesional_pre-dose25.4222
GSM1296117P_lesional_pre-dose39.7124
GSM1296113Q_lesional_pre-dose44.7824
GSM1296096R_lesional_pre-dose21.0320
GSM1296105S_lesional_pre-dose6.086
GSM1296098T_lesional_pre-dose6.024
GSM1296101U_lesional_pre-dose11.711
GSM1296121V_lesional_pre-dose22.8818
GSM1296088W_lesional_pre-dose20.1319
GSM1296082X_lesional_pre-dose20.0619
GSM1296115Y_lesional_pre-dose30.2722
GSM1296084Z_lesional_pre-dose29.8722
GSM1296072B_lesional_day814.2312
GSM1296069L_lesional_day823.5716
GSM1296071P_lesional_day820.7115
GSM1296070Y_lesional_day831.2621
GSM1296073V_lesional_day829.2821
GSM1296034A_lesional_day1525.1920
GSM1296041G_lesional_day1534.823
GSM1296035R_lesional_day1522.9622
GSM1296038U_lesional_day151.481
GSM1296047B_lesional_day1544.526
GSM1296039E_lesional_day1566.3335
GSM1296042H_lesional_day1532.9721
GSM1296043L_lesional_day1518.5613
GSM1296037M_lesional_day1528.6421
GSM1296046P_lesional_day1533.8321
GSM1296044Q_lesional_day1524.8118
GSM1296045Y_lesional_day1527.1817
GSM1296025C_lesional_day1518.7916
GSM1296033D_lesional_day1522.6420
GSM1296027I_lesional_day1510.913
GSM1296032J_lesional_day1517.6117
GSM1296024K_lesional_day1532.8226
GSM1296031W_lesional_day1512.1312
GSM1296028X_lesional_day1538.8328
GSM1296029Z_lesional_day155.986
GSM1296026F_lesional_day1518.7716
GSM1296030O_lesional_day156.838
GSM1296040S_lesional_day1531.9424
GSM1296036T_lesional_day1533.724
GSM1296048V_lesional_day1535.4924
GSM1296059A_lesional_day431.922
GSM1296066G_lesional_day4340.3625
GSM1296060R_lesional_day4326.6122
GSM1296063U_lesional_day4315.9715
GSM1296064E_lesional_day4310.0910
GSM1296067H_lesional_day4340.6325
GSM1296062M_lesional_day4317.217
GSM1296068Q_lesional_day4320.5114
GSM1296050C_lesional_day432519
GSM1296057D_lesional_day43
GSM1296052I_lesional_day4314.0215
GSM1296054J_lesional_day4326.9221
GSM1296049K_lesional_day4315.0314
GSM1296055W_lesional_day4336.1225
GSM1296053X_lesional_day439.8710
GSM1296058Z_lesional_day4329.1925
GSM1296051F_lesional_day430.881
GSM1296056O_lesional_day4339.4229
GSM1296065S_lesional_day439.510
GSM1296061T_lesional_day432.582
GSM1296095A_non-lesional_pre-dose1.141
GSM1296120B_non-lesional_pre-dose24.7518
GSM1296077C_non-lesional_pre-dose27.3523
GSM1296093D_non-lesional_pre-dose11.8311
GSM1296104E_non-lesional_pre-dose23.5919
GSM1296079F_non-lesional_pre-dose13.2112
GSM1296108G_non-lesional_pre-dose35.9324
GSM1296110H_non-lesional_pre-dose10.88
GSM1296081I_non-lesional_pre-dose13.6415
GSM1296091J_non-lesional_pre-dose15.1915
GSM1296075K_non-lesional_pre-dose33.7325
GSM1296112L_non-lesional_pre-dose28.9318
GSM1296100M_non-lesional_pre-dose17.1816
GSM1296087O_non-lesional_pre-dose9.7910
GSM1296118P_non-lesional_pre-dose26.8118
GSM1296114Q_non-lesional_pre-dose35.1822
GSM1296097R_non-lesional_pre-dose14.5715
GSM1296106S_non-lesional_pre-dose24.9320
GSM1296102U_non-lesional_pre-dose8.258
GSM1296122V_non-lesional_pre-dose28.2920
GSM1296089W_non-lesional_pre-dose37.9625
GSM1296083X_non-lesional_pre-dose11.3512
GSM1296116Y_non-lesional_pre-dose36.9422
GSM1296085Z_non-lesional_pre-dose20.0817