ProfileGDS5420 / 1565821_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 49% 49% 42% 38% 46% 40% 56% 58% 40% 42% 50% 58% 44% 41% 55% 61% 49% 41% 51% 48% 52% 34% 44% 54% 48% 50% 61% 53% 58% 51% 46% 62% 47% 44% 52% 42% 60% 60% 34% 57% 57% 60% 45% 36% 39% 39% 41% 32% 31% 46% 37% 39% 38% 52% 50% 43% 59% 43% 44% 48% 54% 45% 57% 33% 31% 30% 43% 43% 36% 40% 37% 36% 38% 39% 52% 42% 51% 44% 38% 41% 31% 53% 59% 22% 38% 45% 59% 39% 39% 58% 61% 43% 46% 49% 49% 39% 36% 61% 41% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose165.8149
GSM1296119B_lesional_pre-dose173.2649
GSM1296076C_lesional_pre-dose97.842
GSM1296092D_lesional_pre-dose67.1738
GSM1296103E_lesional_pre-dose131.9446
GSM1296078F_lesional_pre-dose82.8840
GSM1296107G_lesional_pre-dose249.9456
GSM1296109H_lesional_pre-dose304.558
GSM1296080I_lesional_pre-dose82.8640
GSM1296090J_lesional_pre-dose93.1442
GSM1296074K_lesional_pre-dose151.6250
GSM1296111L_lesional_pre-dose284.2558
GSM1296099M_lesional_pre-dose118.6944
GSM1296086O_lesional_pre-dose91.5641
GSM1296117P_lesional_pre-dose248.8955
GSM1296113Q_lesional_pre-dose353.2961
GSM1296096R_lesional_pre-dose161.9349
GSM1296105S_lesional_pre-dose104.141
GSM1296098T_lesional_pre-dose192.9351
GSM1296101U_lesional_pre-dose157.9448
GSM1296121V_lesional_pre-dose194.5452
GSM1296088W_lesional_pre-dose58.7734
GSM1296082X_lesional_pre-dose103.0944
GSM1296115Y_lesional_pre-dose233.7754
GSM1296084Z_lesional_pre-dose149.5248
GSM1296072B_lesional_day8179.1550
GSM1296069L_lesional_day8347.7461
GSM1296071P_lesional_day8237.6253
GSM1296070Y_lesional_day8298.8958
GSM1296073V_lesional_day8183.7651
GSM1296034A_lesional_day15148.9346
GSM1296041G_lesional_day15356.0562
GSM1296035R_lesional_day15142.1447
GSM1296038U_lesional_day15118.7144
GSM1296047B_lesional_day15214.9852
GSM1296039E_lesional_day1599.2142
GSM1296042H_lesional_day15333.6160
GSM1296043L_lesional_day15329.0760
GSM1296037M_lesional_day1566.7934
GSM1296046P_lesional_day15279.457
GSM1296044Q_lesional_day15282.457
GSM1296045Y_lesional_day15340.2560
GSM1296025C_lesional_day15120.6445
GSM1296033D_lesional_day1567.0436
GSM1296027I_lesional_day1573.2439
GSM1296032J_lesional_day1587.5339
GSM1296024K_lesional_day1594.3941
GSM1296031W_lesional_day1556.532
GSM1296028X_lesional_day1547.8431
GSM1296029Z_lesional_day15132.5846
GSM1296026F_lesional_day1573.8537
GSM1296030O_lesional_day1571.4239
GSM1296040S_lesional_day1581.3638
GSM1296036T_lesional_day15213.8152
GSM1296048V_lesional_day15176.8650
GSM1296059A_lesional_day43104.0943
GSM1296066G_lesional_day43315.1159
GSM1296060R_lesional_day43108.4143
GSM1296063U_lesional_day43122.2544
GSM1296064E_lesional_day43143.6148
GSM1296067H_lesional_day43245.6354
GSM1296062M_lesional_day43126.6645
GSM1296068Q_lesional_day43285.6557
GSM1296050C_lesional_day4360.5133
GSM1296057D_lesional_day4349.1231
GSM1296052I_lesional_day4339.9530
GSM1296054J_lesional_day43112.8643
GSM1296049K_lesional_day43107.4843
GSM1296055W_lesional_day4376.9336
GSM1296053X_lesional_day4389.0740
GSM1296058Z_lesional_day4370.6537
GSM1296051F_lesional_day4366.7936
GSM1296056O_lesional_day4371.7838
GSM1296065S_lesional_day4386.8439
GSM1296061T_lesional_day43196.7852
GSM1296095A_non-lesional_pre-dose98.1642
GSM1296120B_non-lesional_pre-dose193.5651
GSM1296077C_non-lesional_pre-dose114.2844
GSM1296093D_non-lesional_pre-dose85.6638
GSM1296104E_non-lesional_pre-dose98.0841
GSM1296079F_non-lesional_pre-dose49.4731
GSM1296108G_non-lesional_pre-dose217.853
GSM1296110H_non-lesional_pre-dose326.7259
GSM1296081I_non-lesional_pre-dose22.2622
GSM1296091J_non-lesional_pre-dose75.8338
GSM1296075K_non-lesional_pre-dose112.9845
GSM1296112L_non-lesional_pre-dose325.5759
GSM1296100M_non-lesional_pre-dose91.9739
GSM1296087O_non-lesional_pre-dose72.1839
GSM1296118P_non-lesional_pre-dose308.6758
GSM1296114Q_non-lesional_pre-dose357.3461
GSM1296097R_non-lesional_pre-dose112.9343
GSM1296106S_non-lesional_pre-dose142.8646
GSM1296102U_non-lesional_pre-dose170.9449
GSM1296122V_non-lesional_pre-dose179.9449
GSM1296089W_non-lesional_pre-dose91.7339
GSM1296083X_non-lesional_pre-dose68.7336
GSM1296116Y_non-lesional_pre-dose354.6161
GSM1296085Z_non-lesional_pre-dose95.7141