ProfileGDS5420 / 1564378_a_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 76% 89% 77% 68% 74% 71% 91% 86% 67% 74% 79% 92% 75% 75% 94% 95% 70% 71% 81% 71% 89% 73% 74% 92% 76% 86% 89% 92% 88% 86% 67% 93% 63% 78% 89% 79% 93% 93% 63% 89% 94% 90% 62% 67% 66% 71% 65% 77% 66% 70% 75% 68% 58% 85% 86% 67% 93% 69% 79% 82% 90% 76% 93% 68% 63% 64% 72% 65% 77% 65% 60% 70% 63% 66% 79% 71% 89% 60% 64% 72% 63% 92% 93% 50% 67% 80% 91% 58% 62% 92% 96% 60% 75% 73% 85% 76% 53% 90% 61% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose817.1676
GSM1296119B_lesional_pre-dose1964.8489
GSM1296076C_lesional_pre-dose893.877
GSM1296092D_lesional_pre-dose487.8568
GSM1296103E_lesional_pre-dose731.4974
GSM1296078F_lesional_pre-dose596.171
GSM1296107G_lesional_pre-dose2363.8991
GSM1296109H_lesional_pre-dose1514.0486
GSM1296080I_lesional_pre-dose466.1767
GSM1296090J_lesional_pre-dose738.674
GSM1296074K_lesional_pre-dose978.0279
GSM1296111L_lesional_pre-dose2458.3892
GSM1296099M_lesional_pre-dose762.2275
GSM1296086O_lesional_pre-dose758.5475
GSM1296117P_lesional_pre-dose2906.9494
GSM1296113Q_lesional_pre-dose3081.3395
GSM1296096R_lesional_pre-dose562.6170
GSM1296105S_lesional_pre-dose610.1271
GSM1296098T_lesional_pre-dose1147.8481
GSM1296101U_lesional_pre-dose613.1671
GSM1296121V_lesional_pre-dose1999.0989
GSM1296088W_lesional_pre-dose678.1373
GSM1296082X_lesional_pre-dose726.9374
GSM1296115Y_lesional_pre-dose2534.0892
GSM1296084Z_lesional_pre-dose838.1976
GSM1296072B_lesional_day81535.0786
GSM1296069L_lesional_day81912.4889
GSM1296071P_lesional_day82314.8992
GSM1296070Y_lesional_day81715.9688
GSM1296073V_lesional_day81680.2786
GSM1296034A_lesional_day15520.3167
GSM1296041G_lesional_day15273493
GSM1296035R_lesional_day15378.4863
GSM1296038U_lesional_day15917.9278
GSM1296047B_lesional_day151952.4289
GSM1296039E_lesional_day15957.4279
GSM1296042H_lesional_day152632.5793
GSM1296043L_lesional_day152693.7793
GSM1296037M_lesional_day15394.0863
GSM1296046P_lesional_day151786.3989
GSM1296044Q_lesional_day152688.6594
GSM1296045Y_lesional_day152023.3790
GSM1296025C_lesional_day15358.6862
GSM1296033D_lesional_day15476.2467
GSM1296027I_lesional_day15438.4566
GSM1296032J_lesional_day15605.6571
GSM1296024K_lesional_day15429.0865
GSM1296031W_lesional_day15885.9577
GSM1296028X_lesional_day15471.366
GSM1296029Z_lesional_day15581.8570
GSM1296026F_lesional_day15774.2275
GSM1296030O_lesional_day15505.3968
GSM1296040S_lesional_day15291.0458
GSM1296036T_lesional_day151396.3385
GSM1296048V_lesional_day151531.2986
GSM1296059A_lesional_day43479.2167
GSM1296066G_lesional_day432709.8893
GSM1296060R_lesional_day43552.6969
GSM1296063U_lesional_day43993.979
GSM1296064E_lesional_day431207.6582
GSM1296067H_lesional_day431972.190
GSM1296062M_lesional_day43822.1276
GSM1296068Q_lesional_day432544.1593
GSM1296050C_lesional_day43484.6768
GSM1296057D_lesional_day43383.9763
GSM1296052I_lesional_day43397.2464
GSM1296054J_lesional_day43654.6572
GSM1296049K_lesional_day43425.7365
GSM1296055W_lesional_day43879.4277
GSM1296053X_lesional_day43424.365
GSM1296058Z_lesional_day43322.7660
GSM1296051F_lesional_day43555.170
GSM1296056O_lesional_day43364.5763
GSM1296065S_lesional_day43457.3966
GSM1296061T_lesional_day431023.8179
GSM1296095A_non-lesional_pre-dose588.7771
GSM1296120B_non-lesional_pre-dose1870.5889
GSM1296077C_non-lesional_pre-dose308.9560
GSM1296093D_non-lesional_pre-dose410.7864
GSM1296104E_non-lesional_pre-dose639.672
GSM1296079F_non-lesional_pre-dose372.9863
GSM1296108G_non-lesional_pre-dose2459.4592
GSM1296110H_non-lesional_pre-dose2473.5693
GSM1296081I_non-lesional_pre-dose161.4950
GSM1296091J_non-lesional_pre-dose466.9367
GSM1296075K_non-lesional_pre-dose1057.5380
GSM1296112L_non-lesional_pre-dose2133.191
GSM1296100M_non-lesional_pre-dose299.3158
GSM1296087O_non-lesional_pre-dose342.5862
GSM1296118P_non-lesional_pre-dose2225.5292
GSM1296114Q_non-lesional_pre-dose3661.9396
GSM1296097R_non-lesional_pre-dose310.3260
GSM1296106S_non-lesional_pre-dose790.4475
GSM1296102U_non-lesional_pre-dose705.1373
GSM1296122V_non-lesional_pre-dose1440.4585
GSM1296089W_non-lesional_pre-dose824.7876
GSM1296083X_non-lesional_pre-dose209.6853
GSM1296116Y_non-lesional_pre-dose2047.8790
GSM1296085Z_non-lesional_pre-dose344.2861