ProfileGDS5420 / 1564207_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 55% 35% 64% 74% 45% 62% 43% 49% 74% 71% 55% 39% 51% 64% 43% 49% 50% 48% 56% 57% 41% 69% 64% 39% 71% 55% 33% 48% 40% 48% 63% 37% 62% 43% 50% 43% 45% 37% 57% 40% 54% 42% 67% 78% 84% 84% 70% 73% 77% 81% 64% 77% 48% 51% 48% 54% 45% 52% 44% 50% 45% 57% 48% 63% 58% 86% 81% 57% 40% 78% 66% 60% 48% 47% 51% 51% 44% 75% 85% 54% 64% 51% 47% 92% 80% 58% 48% 59% 78% 45% 53% 49% 50% 64% 52% 70% 76% 37% 85% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose232.3855
GSM1296119B_lesional_pre-dose76.0435
GSM1296076C_lesional_pre-dose370.8664
GSM1296092D_lesional_pre-dose725.5374
GSM1296103E_lesional_pre-dose120.3645
GSM1296078F_lesional_pre-dose332.1462
GSM1296107G_lesional_pre-dose123.2743
GSM1296109H_lesional_pre-dose177.1149
GSM1296080I_lesional_pre-dose763.0174
GSM1296090J_lesional_pre-dose618.2771
GSM1296074K_lesional_pre-dose199.355
GSM1296111L_lesional_pre-dose98.8339
GSM1296099M_lesional_pre-dose183.4951
GSM1296086O_lesional_pre-dose388.6764
GSM1296117P_lesional_pre-dose125.3943
GSM1296113Q_lesional_pre-dose182.9449
GSM1296096R_lesional_pre-dose165.9750
GSM1296105S_lesional_pre-dose162.4248
GSM1296098T_lesional_pre-dose258.5756
GSM1296101U_lesional_pre-dose279.4657
GSM1296121V_lesional_pre-dose105.7841
GSM1296088W_lesional_pre-dose540.6469
GSM1296082X_lesional_pre-dose387.6864
GSM1296115Y_lesional_pre-dose92.8339
GSM1296084Z_lesional_pre-dose601.5671
GSM1296072B_lesional_day8244.5255
GSM1296069L_lesional_day871.1733
GSM1296071P_lesional_day8176.0548
GSM1296070Y_lesional_day8107.9240
GSM1296073V_lesional_day8154.648
GSM1296034A_lesional_day15402.8163
GSM1296041G_lesional_day1585.6237
GSM1296035R_lesional_day15354.8562
GSM1296038U_lesional_day15106.8143
GSM1296047B_lesional_day15181.5550
GSM1296039E_lesional_day15109.8243
GSM1296042H_lesional_day15140.8245
GSM1296043L_lesional_day1591.9237
GSM1296037M_lesional_day15271.9257
GSM1296046P_lesional_day15108.240
GSM1296044Q_lesional_day15236.4454
GSM1296045Y_lesional_day15124.3342
GSM1296025C_lesional_day15477.1367
GSM1296033D_lesional_day15928.3478
GSM1296027I_lesional_day151438.4484
GSM1296032J_lesional_day151342.6284
GSM1296024K_lesional_day15577.2870
GSM1296031W_lesional_day15703.8573
GSM1296028X_lesional_day15866.6577
GSM1296029Z_lesional_day151109.6181
GSM1296026F_lesional_day15388.1664
GSM1296030O_lesional_day15880.7577
GSM1296040S_lesional_day15159.3748
GSM1296036T_lesional_day15195.9651
GSM1296048V_lesional_day15155.9848
GSM1296059A_lesional_day43216.1354
GSM1296066G_lesional_day43140.2645
GSM1296060R_lesional_day43191.4752
GSM1296063U_lesional_day43122.2844
GSM1296064E_lesional_day43161.7150
GSM1296067H_lesional_day43145.5845
GSM1296062M_lesional_day43282.157
GSM1296068Q_lesional_day43182.4848
GSM1296050C_lesional_day43364.0763
GSM1296057D_lesional_day43282.6258
GSM1296052I_lesional_day431613.5786
GSM1296054J_lesional_day431151.2181
GSM1296049K_lesional_day43258.9357
GSM1296055W_lesional_day4396.3540
GSM1296053X_lesional_day43974.9378
GSM1296058Z_lesional_day43459.866
GSM1296051F_lesional_day43292.5360
GSM1296056O_lesional_day43140.8748
GSM1296065S_lesional_day43148.747
GSM1296061T_lesional_day43194.951
GSM1296095A_non-lesional_pre-dose180.0551
GSM1296120B_non-lesional_pre-dose134.3144
GSM1296077C_non-lesional_pre-dose765.475
GSM1296093D_non-lesional_pre-dose1449.9685
GSM1296104E_non-lesional_pre-dose226.8754
GSM1296079F_non-lesional_pre-dose398.3764
GSM1296108G_non-lesional_pre-dose195.3251
GSM1296110H_non-lesional_pre-dose164.9547
GSM1296081I_non-lesional_pre-dose2697.1392
GSM1296091J_non-lesional_pre-dose1060.6980
GSM1296075K_non-lesional_pre-dose254.6358
GSM1296112L_non-lesional_pre-dose176.1248
GSM1296100M_non-lesional_pre-dose309.559
GSM1296087O_non-lesional_pre-dose949.578
GSM1296118P_non-lesional_pre-dose145.845
GSM1296114Q_non-lesional_pre-dose229.9853
GSM1296097R_non-lesional_pre-dose165.1249
GSM1296106S_non-lesional_pre-dose191.5950
GSM1296102U_non-lesional_pre-dose426.5764
GSM1296122V_non-lesional_pre-dose211.7152
GSM1296089W_non-lesional_pre-dose573.570
GSM1296083X_non-lesional_pre-dose825.7776
GSM1296116Y_non-lesional_pre-dose93.8537
GSM1296085Z_non-lesional_pre-dose1447.5285