ProfileGDS5420 / 1558448_a_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 78% 56% 49% 54% 69% 44% 61% 63% 71% 52% 51% 53% 65% 56% 55% 62% 63% 69% 80% 75% 57% 62% 55% 57% 70% 63% 55% 61% 61% 55% 91% 57% 69% 63% 62% 60% 56% 59% 79% 63% 62% 58% 74% 61% 61% 73% 76% 70% 70% 70% 59% 60% 77% 83% 57% 70% 60% 66% 57% 58% 66% 79% 60% 58% 70% 65% 75% 66% 59% 75% 70% 49% 63% 61% 84% 67% 60% 69% 85% 61% 62% 61% 63% 88% 57% 51% 63% 84% 55% 67% 63% 64% 74% 76% 66% 70% 88% 61% 69% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose948.1478
GSM1296119B_lesional_pre-dose251.656
GSM1296076C_lesional_pre-dose145.2949
GSM1296092D_lesional_pre-dose197.4154
GSM1296103E_lesional_pre-dose550.0669
GSM1296078F_lesional_pre-dose111.2644
GSM1296107G_lesional_pre-dose329.7261
GSM1296109H_lesional_pre-dose403.6863
GSM1296080I_lesional_pre-dose600.5771
GSM1296090J_lesional_pre-dose176.6452
GSM1296074K_lesional_pre-dose158.2851
GSM1296111L_lesional_pre-dose215.9953
GSM1296099M_lesional_pre-dose433.6465
GSM1296086O_lesional_pre-dose226.1456
GSM1296117P_lesional_pre-dose246.655
GSM1296113Q_lesional_pre-dose365.2662
GSM1296096R_lesional_pre-dose381.0363
GSM1296105S_lesional_pre-dose552.969
GSM1296098T_lesional_pre-dose1074.9480
GSM1296101U_lesional_pre-dose792.0175
GSM1296121V_lesional_pre-dose266.7257
GSM1296088W_lesional_pre-dose345.6662
GSM1296082X_lesional_pre-dose218.2555
GSM1296115Y_lesional_pre-dose27757
GSM1296084Z_lesional_pre-dose567.4870
GSM1296072B_lesional_day8393.0663
GSM1296069L_lesional_day8252.9555
GSM1296071P_lesional_day8362.7461
GSM1296070Y_lesional_day8351.1161
GSM1296073V_lesional_day8230.9755
GSM1296034A_lesional_day152228.5391
GSM1296041G_lesional_day15262.4857
GSM1296035R_lesional_day15540.3569
GSM1296038U_lesional_day15369.5963
GSM1296047B_lesional_day15373.6762
GSM1296039E_lesional_day15315.6360
GSM1296042H_lesional_day15257.6856
GSM1296043L_lesional_day15314.7259
GSM1296037M_lesional_day15958.3879
GSM1296046P_lesional_day15395.4563
GSM1296044Q_lesional_day15385.1462
GSM1296045Y_lesional_day15295.8658
GSM1296025C_lesional_day15745.1774
GSM1296033D_lesional_day15340.2561
GSM1296027I_lesional_day15325.9261
GSM1296032J_lesional_day15698.1373
GSM1296024K_lesional_day15807.2976
GSM1296031W_lesional_day15592.7170
GSM1296028X_lesional_day15574.5170
GSM1296029Z_lesional_day15594.4670
GSM1296026F_lesional_day15289.0159
GSM1296030O_lesional_day15290.5460
GSM1296040S_lesional_day15884.277
GSM1296036T_lesional_day151238.1683
GSM1296048V_lesional_day15269.6257
GSM1296059A_lesional_day43591.4270
GSM1296066G_lesional_day43326.9960
GSM1296060R_lesional_day43444.8366
GSM1296063U_lesional_day43258.8857
GSM1296064E_lesional_day43273.2258
GSM1296067H_lesional_day43470.1166
GSM1296062M_lesional_day431004.2579
GSM1296068Q_lesional_day43334.5660
GSM1296050C_lesional_day43279.3658
GSM1296057D_lesional_day43601.1970
GSM1296052I_lesional_day43421.3165
GSM1296054J_lesional_day43794.6675
GSM1296049K_lesional_day43456.1566
GSM1296055W_lesional_day43312.9359
GSM1296053X_lesional_day43787.4975
GSM1296058Z_lesional_day43586.3670
GSM1296051F_lesional_day43156.4849
GSM1296056O_lesional_day43362.6463
GSM1296065S_lesional_day43350.9361
GSM1296061T_lesional_day431342.3884
GSM1296095A_non-lesional_pre-dose467.0667
GSM1296120B_non-lesional_pre-dose323.7160
GSM1296077C_non-lesional_pre-dose546.9969
GSM1296093D_non-lesional_pre-dose1429.2685
GSM1296104E_non-lesional_pre-dose335.8461
GSM1296079F_non-lesional_pre-dose338.6162
GSM1296108G_non-lesional_pre-dose351.361
GSM1296110H_non-lesional_pre-dose403.1863
GSM1296081I_non-lesional_pre-dose1839.788
GSM1296091J_non-lesional_pre-dose259.3957
GSM1296075K_non-lesional_pre-dose172.9351
GSM1296112L_non-lesional_pre-dose400.9363
GSM1296100M_non-lesional_pre-dose1365.7284
GSM1296087O_non-lesional_pre-dose206.0455
GSM1296118P_non-lesional_pre-dose49867
GSM1296114Q_non-lesional_pre-dose384.3363
GSM1296097R_non-lesional_pre-dose406.664
GSM1296106S_non-lesional_pre-dose720.0674
GSM1296102U_non-lesional_pre-dose811.5376
GSM1296122V_non-lesional_pre-dose441.766
GSM1296089W_non-lesional_pre-dose596.8170
GSM1296083X_non-lesional_pre-dose1790.9188
GSM1296116Y_non-lesional_pre-dose367.1861
GSM1296085Z_non-lesional_pre-dose563.0869