ProfileGDS5420 / 1558348_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 47% 53% 40% 34% 46% 44% 50% 48% 49% 46% 40% 49% 42% 40% 45% 46% 45% 54% 45% 39% 48% 47% 43% 45% 50% 63% 51% 54% 54% 46% 57% 48% 43% 45% 63% 48% 56% 52% 58% 57% 60% 56% 60% 47% 58% 61% 62% 60% 54% 50% 50% 46% 48% 46% 53% 46% 52% 47% 45% 40% 61% 50% 59% 62% 51% 64% 63% 53% 53% 53% 48% 48% 44% 55% 38% 50% 60% 61% 49% 49% 59% 60% 63% 49% 52% 52% 61% 56% 52% 61% 57% 53% 57% 51% 63% 57% 56% 59% 57% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose146.4747
GSM1296119B_lesional_pre-dose218.1753
GSM1296076C_lesional_pre-dose86.3940
GSM1296092D_lesional_pre-dose54.734
GSM1296103E_lesional_pre-dose131.5946
GSM1296078F_lesional_pre-dose107.8944
GSM1296107G_lesional_pre-dose182.8350
GSM1296109H_lesional_pre-dose165.148
GSM1296080I_lesional_pre-dose147.5249
GSM1296090J_lesional_pre-dose125.5846
GSM1296074K_lesional_pre-dose79.2840
GSM1296111L_lesional_pre-dose171.0549
GSM1296099M_lesional_pre-dose101.842
GSM1296086O_lesional_pre-dose85.6640
GSM1296117P_lesional_pre-dose143.4645
GSM1296113Q_lesional_pre-dose157.0946
GSM1296096R_lesional_pre-dose119.8145
GSM1296105S_lesional_pre-dose228.3554
GSM1296098T_lesional_pre-dose134.1845
GSM1296101U_lesional_pre-dose85.9739
GSM1296121V_lesional_pre-dose155.0748
GSM1296088W_lesional_pre-dose134.2447
GSM1296082X_lesional_pre-dose100.6743
GSM1296115Y_lesional_pre-dose134.3145
GSM1296084Z_lesional_pre-dose166.9250
GSM1296072B_lesional_day8376.5663
GSM1296069L_lesional_day8206.1251
GSM1296071P_lesional_day824554
GSM1296070Y_lesional_day8245.9754
GSM1296073V_lesional_day8138.0346
GSM1296034A_lesional_day15284.4357
GSM1296041G_lesional_day15160.5748
GSM1296035R_lesional_day15105.9643
GSM1296038U_lesional_day15128.0745
GSM1296047B_lesional_day15393.8663
GSM1296039E_lesional_day15152.0948
GSM1296042H_lesional_day15268.9156
GSM1296043L_lesional_day15210.0152
GSM1296037M_lesional_day15284.2458
GSM1296046P_lesional_day15286.2257
GSM1296044Q_lesional_day15329.5560
GSM1296045Y_lesional_day15277.6656
GSM1296025C_lesional_day15307.0360
GSM1296033D_lesional_day15144.2447
GSM1296027I_lesional_day15265.2658
GSM1296032J_lesional_day15353.5361
GSM1296024K_lesional_day15347.1162
GSM1296031W_lesional_day15330.3160
GSM1296028X_lesional_day15212.1254
GSM1296029Z_lesional_day15177.0850
GSM1296026F_lesional_day15159.4250
GSM1296030O_lesional_day15115.8346
GSM1296040S_lesional_day15152.8548
GSM1296036T_lesional_day15147.6846
GSM1296048V_lesional_day15212.6753
GSM1296059A_lesional_day43128.2946
GSM1296066G_lesional_day43212.5552
GSM1296060R_lesional_day43139.5747
GSM1296063U_lesional_day43130.3245
GSM1296064E_lesional_day4386.9940
GSM1296067H_lesional_day43364.561
GSM1296062M_lesional_day43173.7750
GSM1296068Q_lesional_day43325.5759
GSM1296050C_lesional_day43350.5262
GSM1296057D_lesional_day43179.7651
GSM1296052I_lesional_day43402.0864
GSM1296054J_lesional_day43392.3863
GSM1296049K_lesional_day43206.7753
GSM1296055W_lesional_day43223.4153
GSM1296053X_lesional_day43211.9953
GSM1296058Z_lesional_day43146.6548
GSM1296051F_lesional_day43143.348
GSM1296056O_lesional_day43110.8544
GSM1296065S_lesional_day43242.0555
GSM1296061T_lesional_day4385.9838
GSM1296095A_non-lesional_pre-dose163.5650
GSM1296120B_non-lesional_pre-dose321.9360
GSM1296077C_non-lesional_pre-dose331.5461
GSM1296093D_non-lesional_pre-dose173.3349
GSM1296104E_non-lesional_pre-dose164.3549
GSM1296079F_non-lesional_pre-dose286.8359
GSM1296108G_non-lesional_pre-dose330.6360
GSM1296110H_non-lesional_pre-dose404.9563
GSM1296081I_non-lesional_pre-dose153.4249
GSM1296091J_non-lesional_pre-dose191.0652
GSM1296075K_non-lesional_pre-dose175.5552
GSM1296112L_non-lesional_pre-dose366.1961
GSM1296100M_non-lesional_pre-dose260.6856
GSM1296087O_non-lesional_pre-dose174.5752
GSM1296118P_non-lesional_pre-dose350.261
GSM1296114Q_non-lesional_pre-dose280.4157
GSM1296097R_non-lesional_pre-dose210.0553
GSM1296106S_non-lesional_pre-dose284.4857
GSM1296102U_non-lesional_pre-dose193.6751
GSM1296122V_non-lesional_pre-dose376.2363
GSM1296089W_non-lesional_pre-dose273.0657
GSM1296083X_non-lesional_pre-dose258.2856
GSM1296116Y_non-lesional_pre-dose324.8559
GSM1296085Z_non-lesional_pre-dose270.0357