ProfileGDS5420 / 1556864_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 51% 45% 28% 28% 48% 8% 40% 44% 31% 11% 13% 40% 43% 27% 46% 41% 45% 44% 57% 53% 48% 34% 29% 38% 39% 51% 42% 50% 43% 39% 56% 41% 46% 42% 55% 43% 43% 42% 52% 49% 48% 43% 33% 30% 34% 32% 32% 40% 40% 33% 31% 44% 48% 44% 48% 43% 53% 42% 42% 51% 50% 46% 42% 47% 35% 43% 45% 43% 46% 42% 18% 45% 43% 48% 49% 50% 31% 40% 46% 38% 48% 51% 28% 38% 42% 51% 59% 24% 52% 47% 50% 53% 56% 48% 42% 38% 48% 38% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose182.0751
GSM1296119B_lesional_pre-dose137.9445
GSM1296076C_lesional_pre-dose42.2328
GSM1296092D_lesional_pre-dose36.2428
GSM1296103E_lesional_pre-dose145.6948
GSM1296078F_lesional_pre-dose9.018
GSM1296107G_lesional_pre-dose101.8540
GSM1296109H_lesional_pre-dose128.344
GSM1296080I_lesional_pre-dose44.0131
GSM1296090J_lesional_pre-dose10.2211
GSM1296074K_lesional_pre-dose12.0213
GSM1296111L_lesional_pre-dose107.1140
GSM1296099M_lesional_pre-dose111.4443
GSM1296086O_lesional_pre-dose35.1227
GSM1296117P_lesional_pre-dose144.846
GSM1296113Q_lesional_pre-dose118.3941
GSM1296096R_lesional_pre-dose123.4945
GSM1296105S_lesional_pre-dose122.8944
GSM1296098T_lesional_pre-dose268.8357
GSM1296101U_lesional_pre-dose210.2553
GSM1296121V_lesional_pre-dose154.5448
GSM1296088W_lesional_pre-dose58.0334
GSM1296082X_lesional_pre-dose39.729
GSM1296115Y_lesional_pre-dose88.8338
GSM1296084Z_lesional_pre-dose86.2839
GSM1296072B_lesional_day8192.6951
GSM1296069L_lesional_day8127.6442
GSM1296071P_lesional_day8200.5950
GSM1296070Y_lesional_day8130.7443
GSM1296073V_lesional_day888.0539
GSM1296034A_lesional_day15273.6756
GSM1296041G_lesional_day15108.3941
GSM1296035R_lesional_day15130.7346
GSM1296038U_lesional_day15102.9242
GSM1296047B_lesional_day15250.9455
GSM1296039E_lesional_day15108.9843
GSM1296042H_lesional_day15130.443
GSM1296043L_lesional_day15123.0542
GSM1296037M_lesional_day15204.7352
GSM1296046P_lesional_day15180.8749
GSM1296044Q_lesional_day15178.5348
GSM1296045Y_lesional_day15135.9743
GSM1296025C_lesional_day1555.633
GSM1296033D_lesional_day1543.8230
GSM1296027I_lesional_day1550.7234
GSM1296032J_lesional_day1554.0432
GSM1296024K_lesional_day1550.0632
GSM1296031W_lesional_day1599.4440
GSM1296028X_lesional_day1589.3540
GSM1296029Z_lesional_day1555.2933
GSM1296026F_lesional_day15
GSM1296030O_lesional_day1540.5931
GSM1296040S_lesional_day15123.4444
GSM1296036T_lesional_day15165.3648
GSM1296048V_lesional_day15127.4844
GSM1296059A_lesional_day43147.7648
GSM1296066G_lesional_day43122.5743
GSM1296060R_lesional_day43208.5753
GSM1296063U_lesional_day43106.6542
GSM1296064E_lesional_day43103.0542
GSM1296067H_lesional_day43205.1751
GSM1296062M_lesional_day43176.950
GSM1296068Q_lesional_day43159.3546
GSM1296050C_lesional_day43103.7642
GSM1296057D_lesional_day43145.2547
GSM1296052I_lesional_day4356.2435
GSM1296054J_lesional_day43113.8743
GSM1296049K_lesional_day43121.5445
GSM1296055W_lesional_day43121.0843
GSM1296053X_lesional_day43137.0946
GSM1296058Z_lesional_day4399.8142
GSM1296051F_lesional_day4321.3518
GSM1296056O_lesional_day43113.7245
GSM1296065S_lesional_day4311743
GSM1296061T_lesional_day43161.8248
GSM1296095A_non-lesional_pre-dose159.4549
GSM1296120B_non-lesional_pre-dose190.2950
GSM1296077C_non-lesional_pre-dose48.431
GSM1296093D_non-lesional_pre-dose98.9140
GSM1296104E_non-lesional_pre-dose131.7546
GSM1296079F_non-lesional_pre-dose78.7638
GSM1296108G_non-lesional_pre-dose166.1148
GSM1296110H_non-lesional_pre-dose213.8751
GSM1296081I_non-lesional_pre-dose36.5628
GSM1296091J_non-lesional_pre-dose73.6738
GSM1296075K_non-lesional_pre-dose98.7342
GSM1296112L_non-lesional_pre-dose214.0451
GSM1296100M_non-lesional_pre-dose306.7859
GSM1296087O_non-lesional_pre-dose27.8224
GSM1296118P_non-lesional_pre-dose216.7752
GSM1296114Q_non-lesional_pre-dose16747
GSM1296097R_non-lesional_pre-dose176.8750
GSM1296106S_non-lesional_pre-dose225.653
GSM1296102U_non-lesional_pre-dose266.6756
GSM1296122V_non-lesional_pre-dose167.9548
GSM1296089W_non-lesional_pre-dose112.6742
GSM1296083X_non-lesional_pre-dose78.3538
GSM1296116Y_non-lesional_pre-dose172.3348
GSM1296085Z_non-lesional_pre-dose79.8638