ProfileGDS5420 / 1556318_s_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 53% 50% 37% 30% 48% 38% 55% 58% 33% 32% 26% 57% 47% 26% 56% 56% 48% 45% 50% 48% 51% 36% 31% 53% 32% 54% 57% 53% 52% 51% 50% 58% 42% 42% 55% 44% 56% 57% 43% 56% 65% 54% 31% 35% 26% 27% 34% 36% 31% 36% 35% 25% 46% 47% 51% 46% 56% 43% 38% 48% 57% 44% 56% 35% 38% 29% 35% 40% 42% 27% 34% 35% 39% 43% 52% 44% 55% 42% 39% 44% 41% 59% 63% 12% 30% 40% 59% 44% 20% 59% 63% 46% 48% 45% 45% 33% 33% 60% 24% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose216.8553
GSM1296119B_lesional_pre-dose180.250
GSM1296076C_lesional_pre-dose73.637
GSM1296092D_lesional_pre-dose40.5730
GSM1296103E_lesional_pre-dose151.148
GSM1296078F_lesional_pre-dose75.2338
GSM1296107G_lesional_pre-dose241.1255
GSM1296109H_lesional_pre-dose298.2258
GSM1296080I_lesional_pre-dose51.1233
GSM1296090J_lesional_pre-dose48.8332
GSM1296074K_lesional_pre-dose31.226
GSM1296111L_lesional_pre-dose277.7857
GSM1296099M_lesional_pre-dose145.2147
GSM1296086O_lesional_pre-dose34.4926
GSM1296117P_lesional_pre-dose263.1656
GSM1296113Q_lesional_pre-dose267.1456
GSM1296096R_lesional_pre-dose148.5748
GSM1296105S_lesional_pre-dose136.1845
GSM1296098T_lesional_pre-dose179.750
GSM1296101U_lesional_pre-dose154.7448
GSM1296121V_lesional_pre-dose193.2851
GSM1296088W_lesional_pre-dose64.5336
GSM1296082X_lesional_pre-dose45.8931
GSM1296115Y_lesional_pre-dose218.1253
GSM1296084Z_lesional_pre-dose56.9732
GSM1296072B_lesional_day8227.2454
GSM1296069L_lesional_day8287.8557
GSM1296071P_lesional_day8234.0253
GSM1296070Y_lesional_day8209.2352
GSM1296073V_lesional_day8177.3751
GSM1296034A_lesional_day15188.1250
GSM1296041G_lesional_day15289.4758
GSM1296035R_lesional_day1597.8442
GSM1296038U_lesional_day15104.442
GSM1296047B_lesional_day15251.6955
GSM1296039E_lesional_day15117.9644
GSM1296042H_lesional_day15269.1356
GSM1296043L_lesional_day15278.2557
GSM1296037M_lesional_day15119.6243
GSM1296046P_lesional_day15263.1656
GSM1296044Q_lesional_day15441.9665
GSM1296045Y_lesional_day15237.8854
GSM1296025C_lesional_day1550.1831
GSM1296033D_lesional_day1564.3735
GSM1296027I_lesional_day1530.5426
GSM1296032J_lesional_day153827
GSM1296024K_lesional_day1558.3234
GSM1296031W_lesional_day1573.736
GSM1296028X_lesional_day1549.4731
GSM1296029Z_lesional_day1567.336
GSM1296026F_lesional_day1563.835
GSM1296030O_lesional_day1526.4325
GSM1296040S_lesional_day15134.7846
GSM1296036T_lesional_day15154.6147
GSM1296048V_lesional_day15186.551
GSM1296059A_lesional_day43125.3246
GSM1296066G_lesional_day43259.756
GSM1296060R_lesional_day43110.8343
GSM1296063U_lesional_day4386.2938
GSM1296064E_lesional_day43146.2348
GSM1296067H_lesional_day43282.7157
GSM1296062M_lesional_day43117.1444
GSM1296068Q_lesional_day43272.3156
GSM1296050C_lesional_day4369.8635
GSM1296057D_lesional_day437838
GSM1296052I_lesional_day4337.5729
GSM1296054J_lesional_day4367.6135
GSM1296049K_lesional_day4392.8140
GSM1296055W_lesional_day43113.9242
GSM1296053X_lesional_day4338.9527
GSM1296058Z_lesional_day4354.8734
GSM1296051F_lesional_day4362.6935
GSM1296056O_lesional_day4378.8139
GSM1296065S_lesional_day43114.2743
GSM1296061T_lesional_day43202.0352
GSM1296095A_non-lesional_pre-dose112.9644
GSM1296120B_non-lesional_pre-dose248.8155
GSM1296077C_non-lesional_pre-dose94.8442
GSM1296093D_non-lesional_pre-dose89.1239
GSM1296104E_non-lesional_pre-dose119.8344
GSM1296079F_non-lesional_pre-dose93.9441
GSM1296108G_non-lesional_pre-dose304.6359
GSM1296110H_non-lesional_pre-dose400.0363
GSM1296081I_non-lesional_pre-dose10.5312
GSM1296091J_non-lesional_pre-dose44.2530
GSM1296075K_non-lesional_pre-dose86.5140
GSM1296112L_non-lesional_pre-dose328.2659
GSM1296100M_non-lesional_pre-dose128.0444
GSM1296087O_non-lesional_pre-dose21.0720
GSM1296118P_non-lesional_pre-dose313.2759
GSM1296114Q_non-lesional_pre-dose401.4463
GSM1296097R_non-lesional_pre-dose133.6246
GSM1296106S_non-lesional_pre-dose169.8248
GSM1296102U_non-lesional_pre-dose138.3645
GSM1296122V_non-lesional_pre-dose137.7645
GSM1296089W_non-lesional_pre-dose63.1533
GSM1296083X_non-lesional_pre-dose55.5633
GSM1296116Y_non-lesional_pre-dose334.6660
GSM1296085Z_non-lesional_pre-dose31.8324