ProfileGDS5420 / 1555246_a_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 11% 14% 12% 15% 7% 21% 9% 1% 3% 11% 17% 11% 19% 9% 17% 9% 3% 21% 4% 17% 26% 19% 5% 20% 15% 10% 5% 17% 12% 21% 9% 15% 4% 13% 15% 16% 11% 3% 7% 8% 12% 17% 12% 9% 5% 13% 12% 2% 24% 12% 16% 14% 20% 18% 13% 10% 3% 11% 15% 8% 16% 12% 13% 10% 18% 9% 8% 13% 19% 16% 3% 25% 17% 18% 15% 9% 15% 9% 1% 12% 14% 13% 21% 12% 8% 1% 3% 3% 11% 2% 10% 4% 11% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose10.5611
GSM1296119B_lesional_pre-dose17.9714
GSM1296076C_lesional_pre-dose14.4612
GSM1296092D_lesional_pre-dose14.2615
GSM1296103E_lesional_pre-dose6.727
GSM1296078F_lesional_pre-dose25.8521
GSM1296107G_lesional_pre-dose10.899
GSM1296109H_lesional_pre-dose1.521
GSM1296080I_lesional_pre-dose
GSM1296090J_lesional_pre-dose2.633
GSM1296074K_lesional_pre-dose10.6711
GSM1296111L_lesional_pre-dose25.0617
GSM1296099M_lesional_pre-dose10.9211
GSM1296086O_lesional_pre-dose21.519
GSM1296117P_lesional_pre-dose12.289
GSM1296113Q_lesional_pre-dose27.3717
GSM1296096R_lesional_pre-dose8.079
GSM1296105S_lesional_pre-dose3.493
GSM1296098T_lesional_pre-dose32.8821
GSM1296101U_lesional_pre-dose4.094
GSM1296121V_lesional_pre-dose20.617
GSM1296088W_lesional_pre-dose33.8826
GSM1296082X_lesional_pre-dose19.1519
GSM1296115Y_lesional_pre-dose6.25
GSM1296084Z_lesional_pre-dose26.1120
GSM1296072B_lesional_day817.7215
GSM1296069L_lesional_day814.1710
GSM1296071P_lesional_day87.25
GSM1296070Y_lesional_day824.117
GSM1296073V_lesional_day814.0212
GSM1296034A_lesional_day1527.3621
GSM1296041G_lesional_day1510.889
GSM1296035R_lesional_day1512.7715
GSM1296038U_lesional_day153.764
GSM1296047B_lesional_day1517.0413
GSM1296039E_lesional_day1516.6415
GSM1296042H_lesional_day1522.9416
GSM1296043L_lesional_day1514.4811
GSM1296037M_lesional_day153.833
GSM1296046P_lesional_day159.337
GSM1296044Q_lesional_day1510.068
GSM1296045Y_lesional_day1517.2812
GSM1296025C_lesional_day1519.5417
GSM1296033D_lesional_day1511.4212
GSM1296027I_lesional_day157.849
GSM1296032J_lesional_day15
GSM1296024K_lesional_day155.195
GSM1296031W_lesional_day1513.7113
GSM1296028X_lesional_day1511.6112
GSM1296029Z_lesional_day151.912
GSM1296026F_lesional_day1532.8424
GSM1296030O_lesional_day159.7112
GSM1296040S_lesional_day1517.9316
GSM1296036T_lesional_day1516.6814
GSM1296048V_lesional_day1526.8220
GSM1296059A_lesional_day4318.2818
GSM1296066G_lesional_day4315.9413
GSM1296060R_lesional_day439.2310
GSM1296063U_lesional_day433.763
GSM1296064E_lesional_day43
GSM1296067H_lesional_day4312.9711
GSM1296062M_lesional_day4314.4215
GSM1296068Q_lesional_day4312.158
GSM1296050C_lesional_day4320.2916
GSM1296057D_lesional_day4310.7812
GSM1296052I_lesional_day4311.8213
GSM1296054J_lesional_day4310.8910
GSM1296049K_lesional_day4320.7118
GSM1296055W_lesional_day439.059
GSM1296053X_lesional_day438.168
GSM1296058Z_lesional_day4311.213
GSM1296051F_lesional_day4322.5719
GSM1296056O_lesional_day4315.3516
GSM1296065S_lesional_day432.793
GSM1296061T_lesional_day4335.3325
GSM1296095A_non-lesional_pre-dose18.4617
GSM1296120B_non-lesional_pre-dose24.818
GSM1296077C_non-lesional_pre-dose16.4815
GSM1296093D_non-lesional_pre-dose
GSM1296104E_non-lesional_pre-dose
GSM1296079F_non-lesional_pre-dose9.919
GSM1296108G_non-lesional_pre-dose17.3415
GSM1296110H_non-lesional_pre-dose11.249
GSM1296081I_non-lesional_pre-dose0.661
GSM1296091J_non-lesional_pre-dose11.2312
GSM1296075K_non-lesional_pre-dose15.5114
GSM1296112L_non-lesional_pre-dose19.313
GSM1296100M_non-lesional_pre-dose
GSM1296087O_non-lesional_pre-dose22.9621
GSM1296118P_non-lesional_pre-dose16.0912
GSM1296114Q_non-lesional_pre-dose10.638
GSM1296097R_non-lesional_pre-dose0.821
GSM1296106S_non-lesional_pre-dose3.13
GSM1296102U_non-lesional_pre-dose2.923
GSM1296122V_non-lesional_pre-dose14.2511
GSM1296089W_non-lesional_pre-dose2.342
GSM1296083X_non-lesional_pre-dose9.2510
GSM1296116Y_non-lesional_pre-dose5.924
GSM1296085Z_non-lesional_pre-dose11.3811