ProfileGDS5420 / 1554772_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 24% 31% 19% 18% 5% 19% 28% 17% 15% 14% 14% 28% 13% 21% 30% 36% 20% 10% 19% 1% 31% 18% 23% 29% 23% 31% 31% 31% 32% 25% 23% 18% 8% 30% 16% 33% 33% 7% 33% 34% 32% 33% 19% 20% 21% 10% 31% 10% 17% 19% 41% 14% 26% 24% 5% 28% 17% 25% 22% 34% 20% 38% 30% 20% 24% 29% 32% 9% 16% 20% 17% 29% 30% 28% 33% 30% 21% 24% 28% 33% 5% 23% 28% 35% 3% 35% 40% 41% 14% 27% 9% 33% 12% 16% 36% 16% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose31.2524
GSM1296119B_lesional_pre-dose57.1931
GSM1296076C_lesional_pre-dose2419
GSM1296092D_lesional_pre-dose18.0318
GSM1296103E_lesional_pre-dose5.045
GSM1296078F_lesional_pre-dose22.9519
GSM1296107G_lesional_pre-dose47.6128
GSM1296109H_lesional_pre-dose21.6717
GSM1296080I_lesional_pre-dose14.5415
GSM1296090J_lesional_pre-dose13.3714
GSM1296074K_lesional_pre-dose13.8514
GSM1296111L_lesional_pre-dose50.6528
GSM1296099M_lesional_pre-dose13.2813
GSM1296086O_lesional_pre-dose24.8321
GSM1296117P_lesional_pre-dose58.8830
GSM1296113Q_lesional_pre-dose89.4336
GSM1296096R_lesional_pre-dose21.4120
GSM1296105S_lesional_pre-dose10.410
GSM1296098T_lesional_pre-dose28.9119
GSM1296101U_lesional_pre-dose0.661
GSM1296121V_lesional_pre-dose54.4831
GSM1296088W_lesional_pre-dose19.118
GSM1296082X_lesional_pre-dose26.2123
GSM1296115Y_lesional_pre-dose51.2629
GSM1296084Z_lesional_pre-dose30.9423
GSM1296072B_lesional_day856.2131
GSM1296069L_lesional_day864.9431
GSM1296071P_lesional_day864.4731
GSM1296070Y_lesional_day864.8832
GSM1296073V_lesional_day837.0525
GSM1296034A_lesional_day15
GSM1296041G_lesional_day1533.5923
GSM1296035R_lesional_day1516.8218
GSM1296038U_lesional_day158.078
GSM1296047B_lesional_day1556.0330
GSM1296039E_lesional_day1518.8816
GSM1296042H_lesional_day1568.0933
GSM1296043L_lesional_day157233
GSM1296037M_lesional_day157.737
GSM1296046P_lesional_day1571.833
GSM1296044Q_lesional_day1573.8934
GSM1296045Y_lesional_day1571.6232
GSM1296025C_lesional_day1555.4833
GSM1296033D_lesional_day1520.0819
GSM1296027I_lesional_day1519.0720
GSM1296032J_lesional_day1524.121
GSM1296024K_lesional_day159.6810
GSM1296031W_lesional_day1551.4731
GSM1296028X_lesional_day159.4810
GSM1296029Z_lesional_day1517.317
GSM1296026F_lesional_day1524.4319
GSM1296030O_lesional_day1580.9441
GSM1296040S_lesional_day1515.5214
GSM1296036T_lesional_day1539.726
GSM1296048V_lesional_day1536.424
GSM1296059A_lesional_day434.845
GSM1296066G_lesional_day4351.4328
GSM1296060R_lesional_day4318.4317
GSM1296063U_lesional_day4334.0825
GSM1296064E_lesional_day4326.5122
GSM1296067H_lesional_day4373.6734
GSM1296062M_lesional_day4322.7620
GSM1296068Q_lesional_day43103.1638
GSM1296050C_lesional_day4351.3330
GSM1296057D_lesional_day4320.8420
GSM1296052I_lesional_day4326.4524
GSM1296054J_lesional_day4346.3129
GSM1296049K_lesional_day4353.9332
GSM1296055W_lesional_day43
GSM1296053X_lesional_day438.399
GSM1296058Z_lesional_day4314.6616
GSM1296051F_lesional_day4324.7220
GSM1296056O_lesional_day4316.4517
GSM1296065S_lesional_day4343.529
GSM1296061T_lesional_day4348.1530
GSM1296095A_non-lesional_pre-dose40.5728
GSM1296120B_non-lesional_pre-dose69.7633
GSM1296077C_non-lesional_pre-dose43.4530
GSM1296093D_non-lesional_pre-dose26.3621
GSM1296104E_non-lesional_pre-dose
GSM1296079F_non-lesional_pre-dose33.2124
GSM1296108G_non-lesional_pre-dose47.3828
GSM1296110H_non-lesional_pre-dose69.7733
GSM1296081I_non-lesional_pre-dose4.445
GSM1296091J_non-lesional_pre-dose27.2223
GSM1296075K_non-lesional_pre-dose39.2528
GSM1296112L_non-lesional_pre-dose85.2235
GSM1296100M_non-lesional_pre-dose3.443
GSM1296087O_non-lesional_pre-dose55.1835
GSM1296118P_non-lesional_pre-dose113.9940
GSM1296114Q_non-lesional_pre-dose114.0741
GSM1296097R_non-lesional_pre-dose14.1514
GSM1296106S_non-lesional_pre-dose42.3327
GSM1296102U_non-lesional_pre-dose9.499
GSM1296122V_non-lesional_pre-dose69.7633
GSM1296089W_non-lesional_pre-dose14.2812
GSM1296083X_non-lesional_pre-dose16.1316
GSM1296116Y_non-lesional_pre-dose89.3336
GSM1296085Z_non-lesional_pre-dose17.9216