ProfileGDS5420 / 1552777_a_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 51% 56% 52% 62% 52% 68% 57% 72% 44% 59% 53% 66% 53% 58% 70% 59% 68% 42% 56% 56% 56% 43% 72% 64% 45% 49% 54% 53% 61% 60% 42% 67% 66% 56% 39% 60% 65% 53% 39% 53% 46% 50% 44% 35% 28% 28% 32% 24% 32% 40% 52% 49% 50% 42% 56% 56% 61% 57% 59% 66% 37% 38% 39% 34% 41% 24% 32% 29% 35% 36% 48% 54% 65% 47% 43% 55% 42% 41% 33% 46% 35% 44% 51% 38% 36% 42% 45% 31% 21% 34% 44% 57% 39% 39% 31% 30% 47% 51% 31% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose188.5751
GSM1296119B_lesional_pre-dose250.8156
GSM1296076C_lesional_pre-dose174.2252
GSM1296092D_lesional_pre-dose325.9962
GSM1296103E_lesional_pre-dose198.5252
GSM1296078F_lesional_pre-dose465.5968
GSM1296107G_lesional_pre-dose263.6157
GSM1296109H_lesional_pre-dose645.6672
GSM1296080I_lesional_pre-dose105.3744
GSM1296090J_lesional_pre-dose290.7859
GSM1296074K_lesional_pre-dose180.9753
GSM1296111L_lesional_pre-dose453.8366
GSM1296099M_lesional_pre-dose206.4553
GSM1296086O_lesional_pre-dose255.158
GSM1296117P_lesional_pre-dose569.3770
GSM1296113Q_lesional_pre-dose315.6859
GSM1296096R_lesional_pre-dose496.9768
GSM1296105S_lesional_pre-dose112.5642
GSM1296098T_lesional_pre-dose253.7356
GSM1296101U_lesional_pre-dose258.9256
GSM1296121V_lesional_pre-dose246.7556
GSM1296088W_lesional_pre-dose103.6543
GSM1296082X_lesional_pre-dose625.6772
GSM1296115Y_lesional_pre-dose409.8964
GSM1296084Z_lesional_pre-dose123.3145
GSM1296072B_lesional_day8170.7449
GSM1296069L_lesional_day8247.3454
GSM1296071P_lesional_day8234.5253
GSM1296070Y_lesional_day8352.3761
GSM1296073V_lesional_day8299.0460
GSM1296034A_lesional_day15111.8542
GSM1296041G_lesional_day15487.4767
GSM1296035R_lesional_day15456.0866
GSM1296038U_lesional_day15254.2556
GSM1296047B_lesional_day1598.4939
GSM1296039E_lesional_day15301.2760
GSM1296042H_lesional_day15428.365
GSM1296043L_lesional_day15223.5353
GSM1296037M_lesional_day1591.2539
GSM1296046P_lesional_day15234.7553
GSM1296044Q_lesional_day15159.0146
GSM1296045Y_lesional_day15193.6550
GSM1296025C_lesional_day15116.5944
GSM1296033D_lesional_day1565.1435
GSM1296027I_lesional_day1534.1828
GSM1296032J_lesional_day1539.428
GSM1296024K_lesional_day1549.1132
GSM1296031W_lesional_day1531.9324
GSM1296028X_lesional_day1551.4332
GSM1296029Z_lesional_day1590.5240
GSM1296026F_lesional_day15180.7952
GSM1296030O_lesional_day15139.3349
GSM1296040S_lesional_day15176.4350
GSM1296036T_lesional_day15115.8142
GSM1296048V_lesional_day15249.3656
GSM1296059A_lesional_day43240.9756
GSM1296066G_lesional_day43351.6461
GSM1296060R_lesional_day43274.0857
GSM1296063U_lesional_day43293.7759
GSM1296064E_lesional_day43429.4166
GSM1296067H_lesional_day4390.4837
GSM1296062M_lesional_day4378.9438
GSM1296068Q_lesional_day43107.139
GSM1296050C_lesional_day4362.4234
GSM1296057D_lesional_day4395.3341
GSM1296052I_lesional_day4326.9824
GSM1296054J_lesional_day4357.3532
GSM1296049K_lesional_day4344.6129
GSM1296055W_lesional_day4368.0235
GSM1296053X_lesional_day4370.8536
GSM1296058Z_lesional_day43142.4348
GSM1296051F_lesional_day4320454
GSM1296056O_lesional_day43405.8865
GSM1296065S_lesional_day43144.2847
GSM1296061T_lesional_day43112.7743
GSM1296095A_non-lesional_pre-dose235.2655
GSM1296120B_non-lesional_pre-dose119.5542
GSM1296077C_non-lesional_pre-dose93.2541
GSM1296093D_non-lesional_pre-dose63.3933
GSM1296104E_non-lesional_pre-dose135.8146
GSM1296079F_non-lesional_pre-dose63.3935
GSM1296108G_non-lesional_pre-dose132.0344
GSM1296110H_non-lesional_pre-dose203.5951
GSM1296081I_non-lesional_pre-dose68.6638
GSM1296091J_non-lesional_pre-dose67.3836
GSM1296075K_non-lesional_pre-dose95.1642
GSM1296112L_non-lesional_pre-dose154.5945
GSM1296100M_non-lesional_pre-dose53.7831
GSM1296087O_non-lesional_pre-dose22.6221
GSM1296118P_non-lesional_pre-dose78.9634
GSM1296114Q_non-lesional_pre-dose136.2844
GSM1296097R_non-lesional_pre-dose263.2157
GSM1296106S_non-lesional_pre-dose95.4539
GSM1296102U_non-lesional_pre-dose92.7839
GSM1296122V_non-lesional_pre-dose62.1331
GSM1296089W_non-lesional_pre-dose52.0730
GSM1296083X_non-lesional_pre-dose144.0847
GSM1296116Y_non-lesional_pre-dose213.6251
GSM1296085Z_non-lesional_pre-dose52.4531