ProfileGDS5420 / 1552719_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 58% 46% 46% 45% 59% 38% 47% 53% 56% 44% 48% 44% 52% 43% 46% 50% 48% 50% 64% 57% 49% 46% 43% 46% 50% 53% 49% 48% 45% 50% 70% 49% 56% 44% 54% 49% 44% 44% 57% 46% 49% 44% 48% 48% 52% 53% 54% 52% 50% 52% 43% 45% 57% 65% 51% 58% 45% 52% 42% 46% 50% 59% 50% 44% 54% 47% 53% 52% 51% 61% 57% 42% 53% 48% 65% 52% 48% 49% 58% 48% 45% 40% 49% 49% 44% 47% 49% 53% 47% 49% 53% 50% 49% 54% 53% 49% 61% 48% 42% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose282.1158
GSM1296119B_lesional_pre-dose142.9246
GSM1296076C_lesional_pre-dose122.6346
GSM1296092D_lesional_pre-dose111.0645
GSM1296103E_lesional_pre-dose294.5359
GSM1296078F_lesional_pre-dose77.438
GSM1296107G_lesional_pre-dose151.8947
GSM1296109H_lesional_pre-dose226.0853
GSM1296080I_lesional_pre-dose240.3256
GSM1296090J_lesional_pre-dose107.7644
GSM1296074K_lesional_pre-dose130.7448
GSM1296111L_lesional_pre-dose133.1944
GSM1296099M_lesional_pre-dose199.8252
GSM1296086O_lesional_pre-dose101.3743
GSM1296117P_lesional_pre-dose144.5546
GSM1296113Q_lesional_pre-dose193.4850
GSM1296096R_lesional_pre-dose148.9148
GSM1296105S_lesional_pre-dose178.1850
GSM1296098T_lesional_pre-dose408.0164
GSM1296101U_lesional_pre-dose268.957
GSM1296121V_lesional_pre-dose166.9449
GSM1296088W_lesional_pre-dose131.0646
GSM1296082X_lesional_pre-dose100.2743
GSM1296115Y_lesional_pre-dose138.5146
GSM1296084Z_lesional_pre-dose173.5950
GSM1296072B_lesional_day8220.2153
GSM1296069L_lesional_day8184.8949
GSM1296071P_lesional_day8174.6348
GSM1296070Y_lesional_day8147.4145
GSM1296073V_lesional_day8167.8250
GSM1296034A_lesional_day15593.0370
GSM1296041G_lesional_day15166.5349
GSM1296035R_lesional_day15248.2756
GSM1296038U_lesional_day15114.1344
GSM1296047B_lesional_day15236.1754
GSM1296039E_lesional_day15158.2849
GSM1296042H_lesional_day15137.9744
GSM1296043L_lesional_day15141.844
GSM1296037M_lesional_day15281.3457
GSM1296046P_lesional_day15153.0446
GSM1296044Q_lesional_day15184.749
GSM1296045Y_lesional_day15143.7744
GSM1296025C_lesional_day15144.4448
GSM1296033D_lesional_day15146.7248
GSM1296027I_lesional_day15176.8252
GSM1296032J_lesional_day15213.6653
GSM1296024K_lesional_day15216.154
GSM1296031W_lesional_day15209.8452
GSM1296028X_lesional_day15169.7750
GSM1296029Z_lesional_day15200.5252
GSM1296026F_lesional_day15105.0543
GSM1296030O_lesional_day15106.3845
GSM1296040S_lesional_day15272.5357
GSM1296036T_lesional_day15434.4465
GSM1296048V_lesional_day15192.6351
GSM1296059A_lesional_day43269.8358
GSM1296066G_lesional_day43142.6745
GSM1296060R_lesional_day43191.6752
GSM1296063U_lesional_day43109.8242
GSM1296064E_lesional_day43132.7146
GSM1296067H_lesional_day43189.3650
GSM1296062M_lesional_day43301.8159
GSM1296068Q_lesional_day43200.0150
GSM1296050C_lesional_day43121.5244
GSM1296057D_lesional_day43229.9254
GSM1296052I_lesional_day43132.9647
GSM1296054J_lesional_day43212.3853
GSM1296049K_lesional_day43197.5152
GSM1296055W_lesional_day43192.851
GSM1296053X_lesional_day43338.0361
GSM1296058Z_lesional_day43267.1857
GSM1296051F_lesional_day43100.4142
GSM1296056O_lesional_day43192.2553
GSM1296065S_lesional_day43152.5948
GSM1296061T_lesional_day43459.0665
GSM1296095A_non-lesional_pre-dose185.7352
GSM1296120B_non-lesional_pre-dose162.3848
GSM1296077C_non-lesional_pre-dose152.0249
GSM1296093D_non-lesional_pre-dose294.4258
GSM1296104E_non-lesional_pre-dose154.3548
GSM1296079F_non-lesional_pre-dose119.6245
GSM1296108G_non-lesional_pre-dose102.3540
GSM1296110H_non-lesional_pre-dose189.4149
GSM1296081I_non-lesional_pre-dose150.6949
GSM1296091J_non-lesional_pre-dose112.6944
GSM1296075K_non-lesional_pre-dose133.9447
GSM1296112L_non-lesional_pre-dose190.0149
GSM1296100M_non-lesional_pre-dose216.1553
GSM1296087O_non-lesional_pre-dose120.2547
GSM1296118P_non-lesional_pre-dose187.7249
GSM1296114Q_non-lesional_pre-dose232.6453
GSM1296097R_non-lesional_pre-dose172.6150
GSM1296106S_non-lesional_pre-dose177.6949
GSM1296102U_non-lesional_pre-dose233.4354
GSM1296122V_non-lesional_pre-dose226.2353
GSM1296089W_non-lesional_pre-dose177.8849
GSM1296083X_non-lesional_pre-dose344.4361
GSM1296116Y_non-lesional_pre-dose171.6148
GSM1296085Z_non-lesional_pre-dose101.4942