ProfileGDS5268 / 59631_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 63% 64% 61% 64% 68% 64% 62% 59% 66% 61% 63% 59% 57% 76% 56% 72% 57% 61% 60% 66% 76% 67% 67% 67% 78% 69% 74% 64% 66% 59% 67% 69% 72% 62% 68% 63% 60% 60% 60% 60% 71% 66% 71% 69% 59% 58% 60% 61% 70% 73% 64% 61% 62% 62% 62% 60% 58% 69% 75% 73% 68% 67% 68% 61% 62% 68% 61% 64% 67% 58% 65% 71% 78% 72% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a63.493863
GSM386436Untreated HCT116 cells, replicate b65.40364
GSM386437Untreated HCT116 cells, replicate d58.616361
GSM386438Untreated HCT116 cells, replicate e65.04564
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b74.708268
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d64.228964
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e61.147762
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f55.2359
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a72.116566
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b58.503761
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d61.768263
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e55.925859
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a51.031757
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c107.66976
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e50.094756
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f88.38772
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a49.687157
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c56.598361
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e55.692260
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f71.308366
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b116.03376
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c74.204667
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d75.274667
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f74.413767
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b118.54978
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c78.844869
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d95.040274
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f64.982264
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c70.816866
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d55.869359
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e73.534367
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f79.595769
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a91.758372
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b61.93962
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e78.119168
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f64.269663
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b59.070660
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c57.100560
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d57.831960
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e57.538660
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c93.99871
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d73.509266
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e92.407971
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f83.901969
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b55.944459
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d53.544158
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e56.503660
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f57.98461
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b81.740170
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c91.911773
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f63.221164
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a58.304561
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b61.645662
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d61.13462
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e60.139162
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b58.133160
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d54.489258
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a84.359769
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d108.78875
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e99.688673
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f80.581768
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a75.072667
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c78.519768
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f58.624161
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b61.350962
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e74.382968
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b60.950761
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c65.252664
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f73.547667
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c53.791458
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d69.560665
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b92.837971
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e122.8378
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f94.539472