ProfileGDS5268 / 244688_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 36% 32% 23% 26% 38% 39% 37% 26% 26% 37% 33% 27% 20% 13% 22% 16% 18% 22% 19% 19% 13% 16% 16% 16% 53% 45% 51% 32% 26% 16% 43% 28% 17% 19% 23% 15% 12% 8% 16% 15% 15% 7% 10% 7% 20% 23% 33% 21% 27% 13% 25% 17% 17% 16% 27% 17% 7% 18% 9% 10% 6% 40% 18% 36% 23% 32% 15% 14% 30% 14% 16% 10% 7% 8% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a25.713336
GSM386436Untreated HCT116 cells, replicate b24.124232
GSM386437Untreated HCT116 cells, replicate d18.969923
GSM386438Untreated HCT116 cells, replicate e20.178426
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b28.242138
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d27.909939
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e26.732137
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f20.036126
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a20.635526
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b26.892737
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d24.335933
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e20.715627
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a17.267120
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c15.472613
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e18.452422
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f16.014116
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a16.51818
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c17.703822
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e16.678519
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f16.639319
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b14.506613
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c15.614916
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d15.327316
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f15.647216
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b44.693353
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c33.518145
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d40.515451
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f23.31932
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c20.629126
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d15.847616
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e32.479743
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f21.939228
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a16.904917
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b17.005219
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e19.142423
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f15.226315
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b14.045212
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c12.8088
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d15.811416
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e15.194115
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c15.286915
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d12.29217
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e13.608410
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f12.09887
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b17.696620
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d19.027123
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e24.626133
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f18.392121
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b21.092627
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c15.000513
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f20.079525
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a16.49417
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b16.52217
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d16.111216
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e21.087427
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b16.144117
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d12.30177
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a16.361618
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d13.55229
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e13.18210
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f11.79386
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a29.518840
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c17.172818
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f26.484436
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b19.462423
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e24.524632
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b15.907615
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c15.972414
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f22.871430
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c15.00314
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d16.092116
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b13.342710
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e12.50667
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f12.90868