ProfileGDS5268 / 243656_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 60% 60% 62% 59% 62% 58% 59% 62% 58% 61% 64% 61% 60% 67% 58% 65% 61% 51% 59% 59% 62% 63% 64% 61% 62% 61% 55% 63% 61% 65% 57% 63% 64% 59% 64% 66% 67% 65% 67% 61% 66% 65% 68% 62% 64% 63% 62% 58% 60% 65% 62% 65% 62% 67% 63% 64% 68% 63% 67% 67% 68% 66% 64% 64% 63% 63% 64% 69% 62% 64% 57% 66% 73% 65% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a56.256960
GSM386436Untreated HCT116 cells, replicate b55.976560
GSM386437Untreated HCT116 cells, replicate d60.701362
GSM386438Untreated HCT116 cells, replicate e54.250959
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b59.113162
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d50.976258
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e53.543159
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f62.230962
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a52.541858
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b57.49661
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d65.079264
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e58.840361
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a57.672260
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c72.137267
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e52.190358
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f68.144765
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a57.384661
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c40.029551
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e53.658159
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f54.550659
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b61.633362
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c62.356863
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d66.286564
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f58.777761
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b58.952562
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c57.690861
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d45.30955
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f61.166863
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c57.905961
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d68.085465
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e49.596657
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f61.673563
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a65.408264
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b55.383759
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e66.376864
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f72.037466
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b74.639167
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c69.35465
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d73.645367
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e58.339261
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c74.915366
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d71.006265
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e83.242368
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f61.950162
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b67.744764
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d64.803863
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e60.581262
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f53.794358
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b54.806260
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c68.870565
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f59.839962
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a67.615165
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b60.741762
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d73.096367
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e62.318763
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b65.092764
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d77.607468
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a64.8863
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d74.830667
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e76.576367
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f80.626668
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a69.910966
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c64.950964
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f64.669264
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b63.428763
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e61.989763
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b66.305664
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c77.970569
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f60.676262
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c66.637664
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d52.615957
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b72.340966
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e95.508973
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f70.163865