ProfileGDS5268 / 241887_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 50% 46% 45% 46% 61% 56% 51% 48% 47% 52% 50% 45% 52% 31% 43% 53% 50% 50% 53% 51% 53% 57% 59% 58% 58% 51% 70% 50% 50% 41% 52% 42% 33% 43% 47% 45% 43% 39% 47% 47% 50% 43% 44% 51% 38% 44% 44% 38% 51% 27% 38% 40% 38% 41% 45% 42% 39% 52% 42% 52% 46% 50% 31% 45% 40% 48% 30% 17% 34% 31% 22% 42% 38% 49% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a39.193950
GSM386436Untreated HCT116 cells, replicate b35.852946
GSM386437Untreated HCT116 cells, replicate d34.592245
GSM386438Untreated HCT116 cells, replicate e35.472646
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b56.232261
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d47.056456
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e41.036951
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f37.700848
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a36.551547
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b41.611152
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d40.34950
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e34.956745
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a42.709152
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c24.445131
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e32.647843
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f43.858453
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a38.890350
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c38.479150
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e44.151553
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f41.228651
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b43.782853
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c51.327657
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d53.977759
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f52.004858
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b51.290258
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c40.209551
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d77.150270
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f39.619550
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c40.507750
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d32.1241
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e41.843152
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f32.072842
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a25.962233
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b33.174243
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e36.710647
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f35.568845
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b34.069143
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c29.937439
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d36.90647
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e36.125647
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c41.334150
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d33.455543
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e34.95244
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f41.351151
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b28.745338
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d33.802944
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e33.77344
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f29.17938
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b41.660151
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c22.26627
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f28.18638
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a30.208940
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b29.17738
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d32.178541
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e34.526245
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b32.388642
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d29.362739
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a42.282552
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d33.248742
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e43.290752
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f35.0746
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a40.464350
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c23.941431
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f33.859345
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b30.482240
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e38.377848
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b23.540830
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c17.439217
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f25.663234
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c24.304931
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d19.095922
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b32.187942
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e30.239738
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f39.751649