ProfileGDS5268 / 241720_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 57% 50% 44% 38% 48% 59% 47% 41% 45% 61% 54% 46% 50% 32% 45% 23% 50% 47% 48% 39% 21% 45% 39% 38% 25% 51% 38% 49% 55% 41% 54% 40% 21% 43% 37% 41% 31% 37% 32% 40% 21% 26% 27% 23% 40% 46% 53% 43% 43% 20% 40% 45% 41% 43% 42% 37% 38% 26% 23% 32% 27% 52% 38% 46% 50% 42% 45% 19% 52% 32% 45% 32% 19% 27% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a49.39157
GSM386436Untreated HCT116 cells, replicate b40.441950
GSM386437Untreated HCT116 cells, replicate d33.470144
GSM386438Untreated HCT116 cells, replicate e28.016938
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b36.717848
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d52.535359
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e36.063947
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f30.534441
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a35.151545
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b57.583361
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d45.437854
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e36.53346
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a40.206250
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c25.171732
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e34.619845
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f19.203923
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a39.885350
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c34.877147
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e36.928148
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f28.942339
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b17.896221
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c34.05845
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d28.392939
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f28.08338
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b20.485125
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c39.73951
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d27.648538
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f38.283649
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c46.393655
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d31.986241
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e45.300854
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f30.384240
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a18.574621
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b32.798243
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e27.987537
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f31.546441
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b24.237331
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c28.631437
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d23.904932
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e29.626940
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c17.653621
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d20.6326
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e21.649827
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f18.869723
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b30.457340
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d36.583146
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e44.381953
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f33.608243
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b32.669843
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c18.296120
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f29.430740
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a35.447245
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b31.546341
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d33.560743
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e32.322942
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b27.464637
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d28.539238
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a20.392926
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d19.743123
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e23.561632
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f20.564527
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a42.223952
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c28.923638
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f35.452746
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b41.978950
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e32.488342
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b36.495645
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c18.494119
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f43.125452
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c24.953832
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d35.602745
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b23.958432
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e17.596419
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f21.277527