ProfileGDS5268 / 237444_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 51% 50% 49% 53% 47% 47% 46% 48% 56% 51% 41% 47% 50% 37% 39% 44% 55% 63% 52% 57% 44% 51% 50% 54% 43% 42% 43% 52% 47% 44% 41% 49% 44% 46% 42% 38% 39% 45% 37% 53% 51% 49% 48% 55% 43% 47% 47% 42% 48% 38% 44% 43% 47% 46% 43% 51% 51% 54% 40% 52% 57% 45% 45% 54% 51% 48% 36% 35% 35% 38% 41% 53% 44% 52% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a40.378251
GSM386436Untreated HCT116 cells, replicate b40.198950
GSM386437Untreated HCT116 cells, replicate d38.602149
GSM386438Untreated HCT116 cells, replicate e44.329953
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b36.486547
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d35.421447
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e34.35246
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f37.512448
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a49.793656
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b40.873851
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d30.815741
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e37.15547
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a40.696750
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c29.379337
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e29.605939
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f34.177544
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a46.517955
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c60.400363
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e42.313352
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f50.654657
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b33.580944
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c41.065951
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d39.495650
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f45.650754
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b32.949643
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c31.262342
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d32.154743
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f41.33652
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c36.618947
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d35.02844
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e30.366941
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f39.10449
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a35.090644
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b36.523246
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e32.133242
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f28.465438
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b30.259839
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c35.694845
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d28.128537
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e44.346353
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c41.707751
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d40.173649
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e39.291548
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f47.398955
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b33.863243
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d36.904947
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e36.192447
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f31.979742
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b38.219348
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c29.886238
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f33.376944
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a33.654143
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b37.198947
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d36.459446
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e33.050743
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b41.45751
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d42.420451
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a46.950554
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d30.849540
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e42.327752
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f50.966957
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a34.774445
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c35.251945
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f45.69454
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b42.164251
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e37.935248
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b28.029836
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c28.034635
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f26.386935
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c29.437838
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d31.73341
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b45.333853
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e35.797744
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f44.101752