ProfileGDS5268 / 231203_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 85% 87% 87% 86% 88% 82% 80% 87% 85% 81% 87% 80% 78% 91% 76% 86% 87% 70% 79% 78% 89% 83% 74% 80% 85% 82% 86% 85% 89% 82% 89% 89% 90% 77% 89% 83% 85% 92% 87% 85% 70% 80% 85% 86% 88% 76% 88% 91% 92% 95% 86% 89% 90% 91% 89% 91% 90% 86% 91% 86% 86% 88% 89% 86% 90% 89% 90% 94% 86% 89% 89% 88% 92% 89% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a229.05685
GSM386436Untreated HCT116 cells, replicate b252.36587
GSM386437Untreated HCT116 cells, replicate d247.47487
GSM386438Untreated HCT116 cells, replicate e228.25686
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b274.83688
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d179.30182
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e161.40380
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f249.87987
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a215.79185
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b166.66781
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d268.73787
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e148.05480
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a138.74278
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c310.72891
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e118.04276
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f218.67586
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a248.6787
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c83.864870
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e148.16779
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f140.77778
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b283.69689
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c186.36583
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d108.20174
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f160.50980
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b213.98785
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c177.50182
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d241.44386
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f227.92185
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c291.45789
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d160.87682
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e293.67989
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f286.39489
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a292.64890
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b124.86777
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e285.99889
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f177.78883
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b210.42885
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c387.14492
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d244.61587
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e227.485
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c91.993370
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d146.51780
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e214.61385
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f232.96986
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b268.55588
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d117.76176
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e281.24888
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f348.77491
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b403.45692
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c477.35295
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f219.7386
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a298.32589
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b321.93590
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d332.01391
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e306.94189
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b340.92491
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d322.09490
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a234.75886
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d343.02191
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e242.84186
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f246.76786
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a287.0588
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c305.98389
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f234.02786
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b313.13990
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e285.19189
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b300.03790
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c439.97594
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f215.95186
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c275.41589
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d287.88489
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b267.84188
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e364.6192
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f277.88589