ProfileGDS5268 / 230705_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 35% 28% 26% 33% 23% 25% 30% 30% 26% 30% 28% 32% 30% 28% 42% 31% 27% 31% 30% 33% 31% 27% 29% 28% 23% 33% 21% 28% 22% 37% 26% 25% 28% 34% 26% 40% 31% 29% 27% 31% 32% 34% 33% 30% 35% 32% 27% 27% 25% 31% 29% 28% 32% 32% 29% 28% 33% 31% 36% 24% 31% 27% 30% 27% 29% 30% 27% 30% 37% 29% 28% 28% 32% 30% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a24.978935
GSM386436Untreated HCT116 cells, replicate b21.184528
GSM386437Untreated HCT116 cells, replicate d20.779826
GSM386438Untreated HCT116 cells, replicate e24.360933
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b18.512523
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d19.395725
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e21.883430
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f22.57230
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a20.627726
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b22.415630
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d21.325128
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e23.716132
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a22.744130
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c22.955828
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e32.374242
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f23.974731
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a20.754127
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c21.850131
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e22.345730
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f24.167833
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b23.239531
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c20.822527
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d21.796329
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f21.253528
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b19.659123
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c24.175633
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d18.050521
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f20.817728
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c18.591422
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d28.242737
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e20.465326
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f20.308825
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a22.699628
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b25.263134
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e20.403826
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f30.72840
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b24.170731
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c22.631929
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d21.414427
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e23.570931
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c24.147532
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d25.37534
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e25.199533
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f22.518330
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b26.929135
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d24.029632
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e20.844727
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f21.167627
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b20.277225
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c24.794631
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f21.926129
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a22.181128
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b24.202832
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d24.598332
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e22.483429
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b21.855328
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d24.92433
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a22.879631
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d27.598336
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e19.387624
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f23.274331
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a21.003827
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c23.518930
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f20.475927
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b22.663329
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e22.984530
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b22.220427
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c24.85830
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f27.616937
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c22.623829
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d22.588228
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b21.736928
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e25.645132
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f23.076530