ProfileGDS5268 / 230272_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 9% 8% 6% 3% 7% 9% 5% 7% 6% 4% 1% 8% 2% 6% 4% 7% 8% 17% 7% 6% 6% 5% 7% 4% 7% 8% 17% 8% 8% 4% 4% 5% 5% 4% 8% 4% 4% 5% 7% 5% 5% 6% 4% 8% 6% 6% 3% 6% 5% 6% 9% 3% 7% 4% 7% 2% 1% 3% 7% 6% 4% 3% 7% 4% 6% 4% 4% 10% 8% 5% 10% 5% 6% 5% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a12.71929
GSM386436Untreated HCT116 cells, replicate b12.40738
GSM386437Untreated HCT116 cells, replicate d11.80886
GSM386438Untreated HCT116 cells, replicate e10.83793
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b12.18417
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d12.74299
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e11.22335
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f12.04087
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a11.73376
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b11.00984
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d9.732261
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e12.52148
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a10.12732
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c12.66576
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e10.92134
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f12.72517
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a12.58048
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c15.31617
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e12.22367
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f11.84246
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b11.7256
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c11.20435
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d11.99217
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f11.08574
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b12.73897
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c12.69128
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d16.283217
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f12.36148
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c12.49088
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d11.03924
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e11.08784
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f11.66865
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a11.67645
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b10.88334
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e12.87468
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f11.0684
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b11.30254
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c11.7695
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d12.17227
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e11.42785
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c11.50675
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d11.92046
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e11.02474
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f12.37918
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b11.74446
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d11.55846
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e10.73193
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f11.99336
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b11.50675
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c12.10866
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f13.0619
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a10.84013
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b12.5567
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d11.15554
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e12.16457
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b10.23652
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d9.669671
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a10.44493
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d12.79277
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e11.84166
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f10.94154
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a10.83913
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c12.57627
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f11.15694
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b12.11276
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e11.27334
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b11.27794
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c14.002510
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f12.81628
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c11.685
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d13.826110
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b11.53855
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e11.99036
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f11.50345