ProfileGDS5268 / 229292_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 80% 76% 75% 78% 80% 79% 79% 78% 76% 79% 78% 77% 78% 84% 78% 82% 81% 81% 80% 80% 84% 84% 84% 85% 87% 82% 84% 80% 77% 72% 80% 78% 77% 74% 76% 77% 74% 79% 78% 78% 85% 80% 77% 85% 76% 76% 78% 75% 77% 73% 76% 73% 70% 70% 75% 82% 81% 88% 83% 84% 86% 79% 74% 77% 76% 79% 74% 68% 73% 73% 67% 81% 79% 81% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a150.52380
GSM386436Untreated HCT116 cells, replicate b116.75776
GSM386437Untreated HCT116 cells, replicate d106.84775
GSM386438Untreated HCT116 cells, replicate e127.03278
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b147.19280
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d145.57679
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e144.0879
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f135.1178
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a117.00176
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b146.95779
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d130.64278
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e126.84877
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a131.8778
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c171.51384
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e133.91578
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f162.39582
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a154.80281
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c180.46381
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e157.37980
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f154.87180
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b190.59984
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c204.28684
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d219.26284
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f227.25585
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b242.68187
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c171.88582
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d192.43884
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f147.36680
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c122.03677
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d93.017272
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e148.30380
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f128.79678
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a118.77977
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b107.50374
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e116.6876
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f118.62377
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b101.57774
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c129.96579
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d133.21878
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e133.47178
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c241.66185
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d150.78880
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e132.77877
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f219.20185
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b117.62276
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d120.99976
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e130.67778
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f107.89975
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b119.6877
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c92.999173
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f112.40376
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a96.686173
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b82.616970
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d84.302570
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e110.81375
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b166.70682
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d154.85781
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a293.53988
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d179.24483
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e199.25984
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f239.97986
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a144.18179
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c101.68774
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f125.27277
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b113.01876
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e129.44479
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b97.867374
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c75.767668
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f96.807173
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c97.773473
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d74.176667
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b163.45581
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e132.45279
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f156.78181