ProfileGDS5268 / 228745_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 82% 77% 78% 79% 83% 83% 81% 77% 76% 80% 77% 76% 80% 63% 78% 74% 83% 83% 79% 80% 83% 85% 85% 87% 83% 78% 86% 82% 79% 73% 81% 77% 67% 74% 75% 72% 74% 80% 80% 80% 85% 80% 83% 85% 72% 78% 77% 73% 79% 67% 76% 75% 72% 72% 75% 78% 78% 88% 75% 86% 86% 79% 69% 81% 75% 74% 70% 53% 72% 69% 69% 86% 75% 83% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a175.98182
GSM386436Untreated HCT116 cells, replicate b128.35177
GSM386437Untreated HCT116 cells, replicate d127.39578
GSM386438Untreated HCT116 cells, replicate e138.00879
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b183.55183
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d187.0983
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e172.5981
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f121.23577
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a114.33776
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b157.01980
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d124.02477
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e117.9676
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a155.44880
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c63.833163
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e137.18678
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f102.3174
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a175.84883
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c198.82983
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e150.11279
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f160.50380
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b182.51483
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c228.36485
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d232.7785
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f277.01487
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b167.80283
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c128.10578
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d225.81386
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f177.40782
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c134.7879
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d98.723773
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e153.89181
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f118.86777
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a74.680867
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b103.62974
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e106.44475
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f93.735272
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b100.44574
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c139.47180
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d147.65580
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e146.85380
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c237.94785
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d150.65180
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e185.33583
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f226.11885
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b94.556372
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d133.20978
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e122.65677
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f95.573973
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b128.45179
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c72.698867
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f111.37676
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a110.11775
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b89.069372
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d92.567372
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e108.39975
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b129.95778
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d129.24678
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a286.19888
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d109.51275
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e237.1986
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f236.21886
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a142.93979
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c79.801869
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f162.18181
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b105.66475
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e99.222874
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b83.286570
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c46.710653
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f90.837972
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c82.756569
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d80.323169
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b222.19786
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e104.8675
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f173.11183