ProfileGDS5268 / 228642_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 50% 54% 47% 50% 55% 50% 51% 53% 53% 50% 50% 51% 51% 55% 50% 59% 55% 55% 62% 59% 59% 52% 59% 53% 67% 60% 60% 51% 54% 43% 58% 55% 54% 45% 57% 42% 44% 48% 48% 50% 55% 48% 46% 48% 51% 45% 52% 47% 57% 53% 49% 57% 54% 53% 53% 56% 51% 54% 52% 53% 53% 55% 54% 49% 53% 52% 53% 65% 63% 61% 58% 50% 55% 54% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a39.183350
GSM386436Untreated HCT116 cells, replicate b46.310954
GSM386437Untreated HCT116 cells, replicate d36.412647
GSM386438Untreated HCT116 cells, replicate e39.586450
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b46.702855
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d38.627650
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e40.8551
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f45.065453
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a43.884153
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b38.893950
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d40.166350
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e42.049851
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a41.822951
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c48.479755
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e40.882350
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f53.113459
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a46.015755
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c45.710455
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e61.214362
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f54.918759
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b54.813459
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c42.007652
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d54.096659
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f43.876553
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b71.277767
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c53.862860
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d53.154560
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f39.783351
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c46.195754
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d33.044543
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e50.913158
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f47.652855
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a47.484654
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b34.94745
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e50.800857
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f32.802742
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b35.300144
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c39.709648
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d38.688448
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e39.845150
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c47.908655
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d38.591948
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e37.088146
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f38.157148
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b42.775651
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d34.550445
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e42.706152
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f37.467247
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b50.19257
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c46.725653
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f38.027649
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a51.001957
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b46.258654
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d45.503753
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e43.84553
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b49.46456
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d42.424951
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a46.250454
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d44.21552
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e45.229353
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f44.995253
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a46.323455
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c46.531554
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f38.081749
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b44.84253
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e43.459452
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b46.495853
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c68.106965
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f62.839663
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c61.388561
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d54.312958
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b41.099850
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e49.486655
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f47.110954