ProfileGDS5268 / 228174_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 65% 68% 61% 66% 74% 70% 70% 63% 67% 68% 64% 69% 64% 67% 68% 71% 69% 72% 74% 75% 72% 74% 77% 74% 86% 71% 83% 69% 63% 52% 68% 70% 70% 61% 67% 61% 62% 62% 69% 72% 69% 68% 68% 70% 68% 68% 71% 60% 73% 70% 66% 62% 62% 59% 61% 69% 67% 70% 66% 66% 68% 74% 69% 70% 68% 71% 65% 54% 68% 63% 67% 67% 61% 67% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a67.417465
GSM386436Untreated HCT116 cells, replicate b76.346668
GSM386437Untreated HCT116 cells, replicate d59.312261
GSM386438Untreated HCT116 cells, replicate e71.332866
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b104.43174
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d84.369170
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e85.575270
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f63.382663
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a75.985967
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b79.585968
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d65.526664
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e82.975669
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a67.595464
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c73.155867
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e78.81268
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f87.057871
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a80.852769
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c94.329872
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e109.61374
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f110.83175
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b92.087572
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c106.01474
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d136.79477
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f107.32374
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b215.28486
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c89.735671
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d170.64783
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f81.265669
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c64.109163
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d44.821952
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e77.196168
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f84.464370
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a82.479570
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b59.022461
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e72.811967
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f59.606661
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b61.447962
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c61.234362
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d81.788969
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e92.565672
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c86.788169
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d80.137368
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e80.595568
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f88.785770
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b79.620468
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d78.389768
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e88.550671
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f57.507560
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b93.53573
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c81.098470
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f70.313366
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a62.085562
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b61.117162
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d56.121759
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e58.034161
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b81.544169
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d75.132767
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a88.330370
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d74.497966
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e72.142266
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f81.080968
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a101.13274
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c80.976369
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f84.276170
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b77.878568
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e86.289471
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b68.040965
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c47.593754
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f76.523368
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c64.087963
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d73.261967
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b76.737367
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e61.056961
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f74.402467