ProfileGDS5268 / 227174_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 75% 73% 74% 75% 78% 75% 76% 74% 72% 76% 78% 74% 73% 71% 76% 77% 74% 79% 80% 78% 85% 86% 87% 85% 83% 78% 83% 76% 72% 77% 75% 76% 76% 72% 77% 77% 77% 71% 80% 74% 88% 85% 87% 86% 70% 74% 74% 71% 79% 74% 75% 74% 75% 77% 76% 77% 69% 86% 87% 86% 88% 80% 69% 77% 74% 81% 75% 73% 77% 72% 70% 88% 87% 87% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a110.81275
GSM386436Untreated HCT116 cells, replicate b98.162673
GSM386437Untreated HCT116 cells, replicate d104.5674
GSM386438Untreated HCT116 cells, replicate e111.54675
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b127.50378
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d109.53775
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e120.00876
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f104.82674
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a95.450272
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b118.79776
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d128.48878
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e106.81574
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a101.97973
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c86.039471
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e121.26876
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f119.61577
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a101.80274
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c151.43179
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e154.09580
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f135.85678
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b211.65585
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c247.19486
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d288.5687
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f226.20885
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b174.67683
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c128.3478
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d174.43483
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f117.91176
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c90.819872
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d120.80477
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e111.10675
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f114.11776
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a112.82476
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b97.351672
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e121.04877
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f120.33677
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b116.65277
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c89.111771
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d144.70380
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e102.67474
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c297.23188
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d204.9185
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e254.0187
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f241.74686
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b85.099370
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d108.74674
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e104.05174
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f88.207371
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b128.49179
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c97.06174
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f102.88975
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a100.78374
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b103.39875
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d113.94377
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e114.59976
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b118.19577
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d83.594669
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a244.08686
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d234.00987
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e240.35586
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f277.23788
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a150.40280
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c80.566269
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f121.89877
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b99.579974
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e145.56981
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b103.18475
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c90.347673
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f119.10477
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c91.863372
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d84.992170
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b267.95788
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e229.96987
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f240.10487