ProfileGDS5268 / 226326_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 83% 82% 84% 84% 86% 85% 85% 84% 85% 85% 84% 84% 83% 80% 81% 86% 85% 84% 84% 84% 86% 87% 88% 88% 91% 86% 89% 85% 84% 81% 86% 84% 83% 83% 81% 82% 81% 80% 84% 82% 87% 86% 84% 86% 82% 83% 84% 82% 85% 82% 81% 79% 81% 82% 80% 83% 82% 86% 84% 86% 85% 84% 84% 84% 83% 86% 78% 75% 84% 75% 74% 84% 84% 82% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a197.8583
GSM386436Untreated HCT116 cells, replicate b170.21582
GSM386437Untreated HCT116 cells, replicate d197.80584
GSM386438Untreated HCT116 cells, replicate e198.82184
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b241.23486
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d220.26185
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e232.96285
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f195.80284
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a210.14785
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b234.1885
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d204.65284
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e207.24384
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a194.08583
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c138.74280
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e166.56381
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f220.71286
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a205.55585
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c215.80284
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e217.88984
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f220.92684
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b231.0186
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c262.89687
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d309.93588
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f288.28888
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b360.34791
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c257.6986
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d322.57689
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f219.14885
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c196.26684
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d149.881
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e230.23486
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f193.99384
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a169.41883
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b186.45583
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e157.13881
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f167.32882
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b151.67781
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c140.75480
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d201.53884
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e176.44782
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c282.11187
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d224.21786
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e213.04684
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f234.33486
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b165.10282
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d190.11483
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e203.87784
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f163.19982
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b198.29685
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c143.89782
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f154.00981
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a133.20279
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b147.89381
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d155.54282
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e151.42780
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b178.74983
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d162.38482
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a232.67886
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d189.6484
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e226.36186
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f213.30985
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a208.1984
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c189.66884
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f205.81684
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b175.56783
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e212.47786
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b122.47278
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c99.855375
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f183.40184
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c105.53575
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d101.37474
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b198.60884
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e177.86484
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f165.54382