ProfileGDS5268 / 225617_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 85% 84% 85% 85% 89% 86% 85% 85% 86% 85% 86% 84% 86% 89% 85% 91% 86% 85% 88% 89% 88% 85% 85% 85% 90% 91% 91% 86% 85% 86% 87% 88% 88% 85% 85% 83% 86% 82% 87% 84% 82% 84% 85% 79% 84% 84% 86% 86% 88% 88% 86% 84% 85% 85% 86% 83% 81% 81% 84% 82% 82% 88% 89% 86% 84% 89% 87% 86% 89% 85% 88% 74% 76% 76% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a231.09685
GSM386436Untreated HCT116 cells, replicate b203.13984
GSM386437Untreated HCT116 cells, replicate d215.31985
GSM386438Untreated HCT116 cells, replicate e209.01385
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b316.95389
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d253.86886
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e225.40485
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f211.45585
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a239.72486
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b230.54685
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d229.86586
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e207.77384
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a242.89586
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c253.36889
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e239.23985
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f374.15791
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a224.87986
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c241.23485
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e294.08588
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f332.40889
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b258.41588
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c222.01885
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d242.16485
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f225.43285
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b327.9190
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c439.43591
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d404.58491
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f248.53186
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c211.1285
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d215.85786
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e245.85487
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f280.07688
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a237.98488
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b233.90585
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e215.74785
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f181.44183
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b218.90786
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c157.72882
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d257.24587
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e202.65584
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c193.51782
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d195.46984
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e224.14685
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f147.31779
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b187.40284
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d210.20884
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e225.73386
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f212.77886
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b260.12988
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c228.52588
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f216.04686
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a180.39684
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b198.30885
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d194.16685
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e229.61186
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b174.68383
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d156.72481
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a164.08881
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d189.28184
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e171.96282
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f174.06782
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a284.43688
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c287.84389
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f230.56386
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b180.8484
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e283.66589
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b216.76687
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c186.15386
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f310.5689
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c201.58485
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d264.08788
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b106.19274
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e114.13676
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f118.12276