ProfileGDS5268 / 225351_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 85% 85% 87% 87% 88% 87% 87% 87% 88% 87% 87% 86% 86% 88% 88% 86% 85% 88% 87% 87% 91% 91% 91% 89% 91% 89% 91% 87% 85% 84% 88% 87% 87% 85% 86% 83% 84% 82% 85% 83% 91% 90% 88% 90% 85% 86% 86% 86% 87% 85% 86% 82% 83% 84% 85% 84% 82% 92% 89% 91% 90% 87% 86% 86% 84% 88% 81% 80% 85% 74% 78% 91% 90% 90% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a228.80685
GSM386436Untreated HCT116 cells, replicate b225.34985
GSM386437Untreated HCT116 cells, replicate d242.19887
GSM386438Untreated HCT116 cells, replicate e259.12487
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b291.4188
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d280.2687
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e287.81287
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f262.65987
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a274.71988
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b286.62487
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d256.28987
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e251.79186
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a241.40586
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c239.8188
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e298.38988
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f223.69586
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a219.58985
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c311.85488
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e285.96287
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f293.04387
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b360.15891
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c391.12691
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d410.05991
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f344.0789
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b395.8791
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c317.00389
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d417.22891
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f277.85587
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c215.33785
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d193.77884
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e284.27388
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f247.74787
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a232.4287
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b233.15485
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e225.78686
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f181.72183
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b192.01884
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c163.37282
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d208.73685
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e187.10983
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c401.52291
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d338.80190
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e295.08888
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f344.62890
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b209.48385
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d250.98386
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e232.33986
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f214.67586
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b237.58287
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c177.75485
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f219.75386
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a156.31882
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b171.68283
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d173.12784
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e208.03285
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b184.07484
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d167.96482
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a412.19692
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d290.8689
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e356.52391
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f347.44890
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a257.93587
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c229.65586
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f240.3386
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b188.3984
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e273.49388
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b142.63581
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c122.77780
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f202.56585
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c103.29974
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d119.79678
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b352.75991
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e301.63490
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f324.21690