ProfileGDS5268 / 225272_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 85% 87% 84% 86% 87% 84% 85% 86% 86% 86% 86% 85% 85% 93% 86% 92% 85% 87% 86% 88% 90% 87% 88% 88% 89% 88% 87% 86% 85% 84% 86% 89% 91% 85% 87% 85% 87% 86% 89% 85% 87% 89% 89% 87% 87% 87% 86% 87% 87% 89% 87% 85% 83% 86% 86% 86% 85% 89% 90% 89% 88% 87% 87% 84% 86% 89% 86% 87% 86% 86% 86% 90% 91% 89% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a232.0985
GSM386436Untreated HCT116 cells, replicate b251.30687
GSM386437Untreated HCT116 cells, replicate d189.43984
GSM386438Untreated HCT116 cells, replicate e231.51386
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b248.62987
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d216.11184
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e242.58885
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f244.17986
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a230.64686
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b254.19586
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d237.60186
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e231.27685
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a219.92485
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c374.71693
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e242.47686
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f425.33992
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a215.43885
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c280.51387
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e244.93786
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f302.7688
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b313.35790
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c260.02887
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d319.38388
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f292.65388
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b318.26889
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c301.21988
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d248.0187
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f237.26986
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c206.00685
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d195.75284
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e225.25286
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f283.61589
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a344.90791
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b218.51185
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e248.64487
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f218.41285
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b244.48887
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c206.64186
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d294.83289
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e226.13985
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c273.51387
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d307.22189
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e326.39589
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f252.30387
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b241.75487
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d260.6187
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e242.7486
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f238.96487
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b237.91887
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c237.57989
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f246.49487
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a206.70785
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b174.35583
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d207.83386
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e231.34186
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b216.73586
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d205.285
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a305.7189
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d319.88490
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e319.55689
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f284.84188
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a263.94187
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c237.2987
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f206.96484
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b214.37286
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e289.16789
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b199.30686
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c195.9587
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f216.05286
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c217.41586
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d206.98486
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b330.0390
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e307.0791
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f269.42489