ProfileGDS5268 / 225143_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 92% 92% 91% 92% 94% 91% 92% 92% 93% 92% 92% 91% 89% 96% 91% 96% 88% 89% 88% 91% 91% 84% 84% 84% 92% 94% 94% 92% 92% 90% 92% 95% 95% 90% 92% 90% 89% 86% 91% 87% 85% 88% 89% 86% 93% 93% 92% 92% 94% 96% 93% 91% 91% 92% 90% 88% 87% 83% 89% 87% 86% 93% 95% 93% 93% 94% 92% 94% 92% 89% 90% 87% 91% 88% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a450.49792
GSM386436Untreated HCT116 cells, replicate b458.91192
GSM386437Untreated HCT116 cells, replicate d366.29391
GSM386438Untreated HCT116 cells, replicate e426.58692
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b538.94994
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d433.51691
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e464.82892
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f447.93692
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a514.82893
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b452.95392
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d428.18792
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e421.94891
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a350.3689
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c674.40896
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e432.06391
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f808.1496
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a275.28488
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c344.5789
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e322.61688
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f439.38491
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b339.00291
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c206.35984
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d220.04484
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f214.72484
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b453.40792
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c656.71394
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d599.55694
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f474.54392
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c412.55892
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d337.20690
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e415.92292
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f643.07195
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a598.11895
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b361.77390
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e433.07692
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f345.20990
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b285.05889
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c212.98286
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d372.09791
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e270.00387
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c244.39985
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d267.3288
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e317.25989
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f245.12186
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b481.82793
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d519.33893
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e432.66792
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f419.95792
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b499.40294
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c555.43396
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f465.47993
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a351.20591
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b352.40691
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d367.97692
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e341.01690
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b263.588
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d247.96287
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a193.93583
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d290.90289
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e258.93787
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f230.96486
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a519.7893
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c590.62395
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f493.29793
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b417.17393
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e544.24194
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b387.17792
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c409.92794
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f421.89992
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c283.27789
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d318.91290
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b239.59487
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e305.16191
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f265.27588