ProfileGDS5268 / 222932_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 32% 40% 30% 39% 28% 37% 38% 32% 27% 35% 34% 35% 27% 17% 30% 26% 27% 35% 25% 21% 22% 33% 31% 39% 23% 22% 22% 48% 32% 30% 38% 24% 18% 30% 26% 30% 30% 22% 27% 32% 36% 27% 33% 45% 32% 38% 43% 32% 20% 23% 30% 35% 26% 29% 30% 32% 27% 31% 27% 36% 36% 35% 26% 48% 32% 25% 27% 22% 28% 14% 17% 30% 25% 31% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a23.295532
GSM386436Untreated HCT116 cells, replicate b29.436840
GSM386437Untreated HCT116 cells, replicate d22.855730
GSM386438Untreated HCT116 cells, replicate e29.155839
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b21.480328
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d27.008737
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e27.970638
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f23.977532
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a20.883527
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b25.503235
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d25.034334
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e25.904235
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a20.643527
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c17.264317
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e22.830430
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f20.864526
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a20.863327
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c24.522135
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e19.614925
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f17.78621
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b18.441422
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c24.397933
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d22.920431
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f28.487839
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b19.291523
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c18.228722
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d18.838622
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f36.911848
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c24.345832
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d23.02730
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e28.278638
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f19.846124
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a17.38218
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b22.764430
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e20.419626
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f22.785430
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b23.230430
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c19.191522
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d21.208827
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e23.936232
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c26.642536
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d21.333127
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e25.3833
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f34.866545
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b24.570532
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d28.335238
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e32.66843
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f24.122332
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b17.920720
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c20.115623
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f22.570630
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a26.197435
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b21.131626
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d22.80329
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e22.963930
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b24.189432
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d21.402727
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a23.077931
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d21.441627
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e26.367936
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f26.788836
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a26.007235
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c20.894626
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f37.566548
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b24.958832
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e20.603825
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b22.060727
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c19.958722
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f21.587628
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c15.291414
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d16.564217
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b22.876930
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e20.72525
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f24.080331