ProfileGDS5268 / 222533_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 75% 76% 74% 73% 76% 75% 77% 74% 74% 75% 76% 76% 76% 68% 75% 73% 77% 79% 78% 75% 79% 81% 82% 82% 82% 75% 82% 78% 70% 70% 75% 71% 72% 72% 75% 72% 73% 75% 75% 74% 78% 79% 81% 82% 74% 75% 74% 74% 74% 66% 72% 69% 66% 71% 71% 74% 71% 83% 79% 80% 81% 74% 68% 75% 70% 75% 62% 57% 69% 59% 64% 79% 74% 78% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a111.04875
GSM386436Untreated HCT116 cells, replicate b114.77176
GSM386437Untreated HCT116 cells, replicate d103.2274
GSM386438Untreated HCT116 cells, replicate e96.61873
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b11476
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d109.94475
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e128.34877
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f106.10374
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a105.85174
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b113.62175
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d113.89476
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e121.39476
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a118.28176
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c77.420368
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e114.89375
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f97.396573
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a119.10877
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c155.52179
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e140.88778
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f111.64475
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b133.60579
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c169.44181
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d187.71382
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f180.57182
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b165.86982
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c110.79575
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d157.11182
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f127.98678
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c84.964770
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d83.511570
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e106.34375
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f88.85171
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a89.401772
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b97.109272
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e107.03975
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f92.64972
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b99.070973
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c106.03675
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d108.9775
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e103.34874
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c141.31878
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d140.81579
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e161.51681
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f173.99782
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b104.5174
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d111.31375
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e103.56674
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f101.02874
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b101.56774
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c70.906666
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f89.657672
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a80.671769
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b69.830966
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d85.672271
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e91.052771
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b101.65374
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d89.121671
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a193.79983
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d132.91579
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e149.86780
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f169.63581
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a101.48474
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c76.866668
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f110.85875
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b85.853970
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e102.98475
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b63.198562
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c53.038857
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f77.766369
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c55.601159
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d67.262464
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b137.96779
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e102.92274
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f126.2578