ProfileGDS5268 / 221949_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 58% 57% 55% 60% 64% 57% 57% 56% 59% 57% 57% 59% 56% 76% 52% 75% 60% 59% 61% 66% 66% 54% 57% 57% 72% 70% 72% 62% 60% 58% 62% 70% 66% 56% 57% 57% 57% 56% 57% 54% 54% 52% 62% 55% 56% 59% 57% 59% 66% 68% 54% 60% 61% 57% 61% 60% 59% 52% 68% 58% 52% 61% 69% 59% 59% 67% 60% 69% 67% 60% 61% 57% 65% 57% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a50.660458
GSM386436Untreated HCT116 cells, replicate b50.468557
GSM386437Untreated HCT116 cells, replicate d47.270755
GSM386438Untreated HCT116 cells, replicate e55.878860
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b63.038664
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d49.453357
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e50.663757
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f48.605856
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a54.753959
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b49.615457
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d50.580757
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e55.952459
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a49.145156
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c110.83976
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e43.818352
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f104.29975
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a55.547360
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c53.243859
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e59.061861
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f70.357666
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b72.166166
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c44.953954
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d51.557857
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f49.575857
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b89.669872
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c82.421270
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d86.375472
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f59.842362
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c56.395860
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d53.718558
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e59.169662
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f84.080970
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a71.996966
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b49.349356
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e49.81357
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f52.255157
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b53.011957
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c50.656
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d51.832457
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e45.80554
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c46.053854
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d44.422952
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e65.628562
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f47.900755
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b50.585856
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d56.412459
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e51.073557
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f55.382459
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b70.542866
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c75.699268
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f44.968254
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a57.490160
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b58.654861
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d51.055357
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e58.240861
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b57.117160
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d56.589959
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a43.467452
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d77.691768
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e52.24658
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f43.045452
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a58.425861
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c82.127769
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f53.686259
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b55.267959
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e71.473467
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b57.84160
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c79.023169
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f73.134167
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c57.579460
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d59.401161
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b52.007157
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e70.361465
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f52.86457