ProfileGDS5268 / 221322_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 19% 16% 17% 13% 19% 19% 16% 19% 17% 18% 18% 18% 17% 37% 15% 28% 23% 25% 19% 19% 19% 14% 17% 16% 27% 22% 26% 18% 20% 15% 23% 24% 18% 13% 23% 16% 21% 20% 21% 17% 22% 18% 15% 17% 17% 19% 17% 19% 20% 19% 16% 19% 21% 16% 23% 20% 20% 14% 13% 17% 15% 21% 18% 25% 18% 24% 23% 33% 18% 21% 19% 19% 20% 21% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a16.462819
GSM386436Untreated HCT116 cells, replicate b15.543716
GSM386437Untreated HCT116 cells, replicate d16.510317
GSM386438Untreated HCT116 cells, replicate e14.588213
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b17.040819
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d16.813819
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e15.383816
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f16.648319
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a16.275217
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b16.220818
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d16.503518
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e16.642718
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a15.987417
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c28.955237
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e15.437615
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f21.823728
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a18.825423
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c18.830825
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e16.639419
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f16.606719
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b17.10119
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c14.818914
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d15.876517
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f15.422616
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b21.71727
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c18.380622
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d20.633526
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f16.314918
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c17.660620
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d15.551715
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e18.684823
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f19.6924
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a17.150318
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b14.581713
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e18.791523
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f15.809316
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b18.215121
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c17.814920
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d18.000321
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e15.915617
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c18.082722
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d16.777518
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e15.554615
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f15.948217
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b16.079717
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d16.996719
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e16.153117
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f17.455319
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b17.928920
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c17.771119
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f15.628216
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a17.167119
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b18.382321
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d16.161516
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e18.914723
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b17.842920
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d17.630120
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a14.779114
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d14.920613
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e15.903117
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f14.886115
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a17.946721
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c17.152518
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f19.504825
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b17.056918
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e20.038724
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b19.832423
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c27.093833
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f16.935118
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c18.432521
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d17.363119
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b17.117919
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e18.15520
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f18.394421