ProfileGDS5268 / 218040_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 87% 88% 89% 89% 89% 89% 89% 88% 87% 87% 87% 88% 87% 85% 88% 88% 88% 88% 89% 88% 86% 85% 87% 85% 92% 89% 91% 89% 87% 84% 89% 87% 85% 86% 85% 86% 86% 86% 88% 87% 85% 85% 88% 84% 88% 88% 90% 89% 87% 84% 87% 80% 81% 81% 85% 87% 87% 82% 80% 83% 84% 88% 86% 88% 87% 89% 79% 71% 83% 83% 80% 83% 81% 83% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a259.63187
GSM386436Untreated HCT116 cells, replicate b274.94988
GSM386437Untreated HCT116 cells, replicate d308.87189
GSM386438Untreated HCT116 cells, replicate e311.43489
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b297.58489
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d327.1889
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e349.64489
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f281.96388
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a247.88187
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b286.10287
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d265.07787
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e309.84388
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a274.44187
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c187.13985
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e299.95688
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f282.96888
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a275.02988
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c315.20988
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e350.96589
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f308.58788
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b218.65886
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c231.66685
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d275.35687
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f231.49585
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b427.69292
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c333.54389
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d378.73691
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f336.37289
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c243.14187
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d184.05184
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e293.80589
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f246.12787
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a192.0385
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b236.15986
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e216.28785
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f235.16786
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b227.29986
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c205.9186
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d275.988
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e258.81487
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c230.63685
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d218.69685
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e280.99488
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f208.68384
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b260.05288
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d303.65188
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e340.06490
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f289.53889
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b243.89587
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c165.73284
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f253.28487
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a139.53180
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b142.39581
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d144.24881
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e214.31985
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b232.05887
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d232.00987
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a174.4282
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d142.40280
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e194.65583
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f199.68784
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a294.24688
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c223.21786
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f277.32188
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b227.45787
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e295.37589
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b130.86979
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c85.489371
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f169.00983
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c170.32783
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d138.53780
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b184.17383
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e149.60981
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f171.53383