ProfileGDS5268 / 212013_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 46% 50% 51% 53% 58% 45% 50% 51% 49% 38% 45% 45% 43% 76% 49% 63% 44% 43% 51% 54% 73% 55% 50% 53% 65% 67% 59% 52% 46% 41% 51% 56% 64% 46% 54% 43% 49% 44% 65% 45% 63% 57% 59% 59% 53% 47% 50% 44% 66% 72% 44% 48% 53% 49% 42% 44% 49% 60% 69% 62% 61% 62% 58% 52% 43% 67% 49% 59% 57% 45% 50% 56% 70% 61% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a34.975646
GSM386436Untreated HCT116 cells, replicate b40.39450
GSM386437Untreated HCT116 cells, replicate d41.618651
GSM386438Untreated HCT116 cells, replicate e44.374153
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b50.628158
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d33.145745
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e39.304850
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f42.328651
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a39.716849
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b27.700238
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d34.41845
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e34.611945
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a32.837643
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c110.63976
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e38.844449
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f61.817463
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a32.491444
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c30.863543
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e41.591451
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f45.543154
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b96.938173
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c46.621355
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d40.098750
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f43.654153
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b66.965765
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c73.034767
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d50.728959
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f41.379552
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c35.908846
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d31.5841
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e41.461251
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f49.392856
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a67.063364
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b36.454946
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e45.72854
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f33.774643
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b40.758649
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c35.445244
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d68.290165
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e34.08645
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c66.87263
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d51.321357
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e58.303959
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f54.778959
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b44.898453
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d36.932947
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e39.523150
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f34.074144
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b68.968966
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c87.32672
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f33.242944
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a38.511148
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b44.400753
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d39.639449
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e32.234242
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b34.056244
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d39.566549
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a57.329760
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d81.751569
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e61.906462
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f60.646661
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a60.629262
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c52.261758
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f42.54952
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b33.523243
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e71.475267
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b41.015949
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c57.173359
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f50.250157
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c36.214245
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d40.992850
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b50.610656
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e84.396570
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f59.820561