ProfileGDS5268 / 206566_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 40% 41% 38% 38% 32% 41% 47% 44% 33% 48% 41% 53% 50% 25% 38% 22% 52% 54% 33% 27% 24% 37% 29% 46% 27% 31% 26% 44% 47% 32% 38% 28% 35% 41% 24% 40% 26% 35% 28% 41% 34% 31% 24% 30% 37% 47% 40% 34% 31% 39% 40% 46% 45% 36% 45% 39% 40% 30% 25% 28% 33% 31% 32% 55% 47% 30% 41% 46% 45% 44% 48% 35% 28% 24% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a28.965640
GSM386436Untreated HCT116 cells, replicate b30.989641
GSM386437Untreated HCT116 cells, replicate d28.283138
GSM386438Untreated HCT116 cells, replicate e28.277738
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b23.87432
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d29.841441
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e35.691347
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f33.382644
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a24.912233
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b37.443848
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d30.630741
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e44.820553
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a40.655950
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c20.863525
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e28.215938
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f18.760822
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a41.333652
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c44.127654
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e24.004733
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f20.905327
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b19.46224
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c26.861937
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d21.748229
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f34.570546
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b21.403127
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c23.15331
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d20.46126
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f32.962544
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c36.688947
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d24.367432
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e28.093738
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f21.80428
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a26.943335
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b30.786141
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e19.355924
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f30.924240
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b21.17526
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c26.613435
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d21.453628
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e30.362441
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c25.080134
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d23.414931
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e19.990724
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f22.838130
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b28.392737
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d37.730147
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e30.225240
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f26.092234
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b23.469731
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c30.844639
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f29.471640
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a36.283646
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b35.685245
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d27.298636
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e35.102845
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b29.503539
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d30.489540
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a22.734830
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d20.672425
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e21.256228
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f24.16533
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a23.34831
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c24.939132
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f47.622355
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b38.389347
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e23.493930
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b32.243541
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c38.222146
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f35.298245
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c34.600944
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d39.055848
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b26.492135
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e22.409628
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f19.6724