ProfileGDS5268 / 205715_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 29% 31% 27% 21% 23% 24% 29% 21% 21% 24% 33% 28% 23% 24% 27% 16% 22% 22% 25% 25% 22% 22% 20% 23% 20% 30% 19% 29% 19% 37% 22% 25% 29% 29% 28% 29% 23% 23% 29% 23% 24% 26% 28% 22% 21% 22% 27% 26% 24% 20% 26% 33% 27% 32% 28% 29% 31% 26% 23% 31% 24% 24% 29% 28% 20% 29% 34% 31% 36% 29% 28% 28% 27% 24% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a21.668229
GSM386436Untreated HCT116 cells, replicate b23.248731
GSM386437Untreated HCT116 cells, replicate d21.015127
GSM386438Untreated HCT116 cells, replicate e17.954521
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b18.827823
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d18.980324
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e21.61129
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f17.859721
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a17.903321
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b19.113124
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d24.117533
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e21.443728
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a18.58623
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c20.494924
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e21.178927
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f16.05216
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a18.484322
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c17.447122
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e19.825525
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f19.396325
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b18.642122
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c18.206422
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d17.353620
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f18.45423
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b18.222320
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c22.095630
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d17.244419
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f21.526129
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c17.237819
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d28.315937
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e18.534422
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f20.32725
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a23.027429
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b22.271329
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e21.718828
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f22.389629
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b19.427723
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c19.510723
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d22.543929
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e18.72123
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c19.166824
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d20.623826
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e22.104728
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f18.175522
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b18.348721
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d18.134422
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e20.954327
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f20.553926
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b19.565524
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c18.182820
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f20.180726
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a25.319433
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b21.609427
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d24.558832
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e21.978728
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b22.05529
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d23.693831
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a19.970626
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d19.640523
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e22.875731
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f19.398824
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a18.988424
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c22.653729
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f21.188328
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b17.925920
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e22.377229
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b26.562134
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c25.340531
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f27.426636
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c22.445829
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d22.575728
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b21.856828
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e22.270727
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f19.870624