ProfileGDS5268 / 202604_x_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 71% 77% 71% 74% 69% 80% 77% 74% 70% 76% 74% 76% 75% 62% 76% 55% 76% 76% 77% 64% 58% 78% 84% 85% 72% 67% 74% 79% 72% 75% 77% 62% 56% 75% 66% 75% 69% 66% 69% 75% 76% 72% 66% 82% 73% 73% 75% 74% 68% 52% 77% 72% 75% 74% 72% 70% 70% 77% 65% 78% 80% 73% 57% 78% 75% 72% 74% 61% 76% 65% 73% 77% 52% 74% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a88.56171
GSM386436Untreated HCT116 cells, replicate b122.69177
GSM386437Untreated HCT116 cells, replicate d87.761471
GSM386438Untreated HCT116 cells, replicate e105.3574
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b80.919869
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d152.65380
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e129.91277
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f103.39374
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a83.564370
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b117.58776
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d103.14874
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e115.73376
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a115.00275
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c62.126562
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e123.4976
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f47.092355
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a113.1976
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c124.12376
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e128.81377
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f67.076664
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b53.222958
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c136.95578
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d214.60984
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f236.44685
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b87.408572
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c71.566367
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d98.389274
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f137.50379
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c91.77472
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d107.66875
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e125.93977
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f59.813262
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a50.646956
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b112.23675
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e70.92366
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f108.01575
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b82.366369
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c71.020866
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d81.329169
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e110.8675
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c127.88576
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d97.302772
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e77.028166
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f174.9782
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b97.964473
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d102.38573
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e112.88575
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f103.95674
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b75.105868
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c45.437352
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f114.33677
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a94.490172
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b107.08275
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d99.367474
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e92.94572
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b86.576670
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d85.517570
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a132.04377
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d69.732865
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e135.00478
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f159.35880
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a99.106873
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c51.672757
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f129.42578
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b105.54975
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e90.595672
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b97.254874
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c59.023561
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f110.48876
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c70.262465
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d96.874373
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b124.23777
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e45.673152
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f102.68674