ProfileGDS5268 / 1569786_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 11% 18% 21% 11% 15% 15% 14% 14% 12% 16% 13% 12% 13% 6% 13% 16% 19% 7% 15% 11% 10% 13% 15% 14% 10% 16% 12% 19% 16% 13% 16% 17% 12% 13% 9% 13% 9% 14% 12% 17% 14% 17% 15% 11% 13% 12% 12% 13% 7% 10% 13% 12% 15% 11% 15% 12% 13% 15% 14% 11% 13% 14% 10% 16% 15% 15% 11% 13% 13% 19% 14% 14% 14% 13% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a13.339211
GSM386436Untreated HCT116 cells, replicate b16.326318
GSM386437Untreated HCT116 cells, replicate d18.132121
GSM386438Untreated HCT116 cells, replicate e13.854211
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b15.049715
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d14.903915
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e14.693414
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f14.721314
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a13.944412
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b15.544216
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d14.50713
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e14.160612
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a14.231113
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c12.59546
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e14.579613
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f15.981816
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a16.938419
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c11.9747
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e14.932115
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f13.729611
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b13.575410
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c14.178913
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d14.950215
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f14.652314
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b13.892610
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c15.761416
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d14.417712
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f16.568519
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c15.794316
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d14.444313
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e15.549116
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f16.510817
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a14.576312
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b14.208613
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e12.9689
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f14.413
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b12.96369
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c15.113714
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d14.083912
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e16.162817
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c14.712114
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d16.04317
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e15.689715
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f13.577811
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b14.588413
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d13.904312
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e14.107812
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f14.780213
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b12.34647
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c13.737710
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f14.72613
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a14.192612
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b15.672915
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d14.156111
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e15.360215
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b14.265812
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d14.862813
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a15.112715
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d15.520514
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e13.704111
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f14.068813
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a14.593214
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c13.497210
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f15.335316
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b15.330715
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e15.546715
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b14.240111
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c15.266513
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f14.657513
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c17.249919
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d15.097414
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b14.820214
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e15.321714
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f14.656613