ProfileGDS5268 / 1569024_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 29% 23% 27% 25% 27% 24% 26% 27% 18% 23% 24% 25% 25% 14% 20% 25% 28% 19% 22% 22% 21% 19% 21% 22% 23% 25% 26% 30% 23% 24% 25% 24% 19% 19% 24% 21% 20% 24% 20% 24% 17% 20% 21% 23% 27% 21% 25% 27% 27% 25% 26% 24% 23% 25% 30% 19% 20% 18% 21% 21% 19% 23% 18% 23% 25% 30% 24% 23% 24% 19% 23% 20% 21% 24% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a21.313129
GSM386436Untreated HCT116 cells, replicate b18.493923
GSM386437Untreated HCT116 cells, replicate d21.315627
GSM386438Untreated HCT116 cells, replicate e20.036925
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b20.967627
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d18.888124
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e20.00926
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f20.68627
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a16.338118
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b18.365923
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d19.18124
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e20.108125
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a19.831125
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c15.888714
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e17.415220
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f20.334925
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a21.225128
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c16.322519
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e18.033222
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f18.369522
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b18.085421
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c16.548219
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d17.500321
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f17.954722
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b19.652923
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c19.643725
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d20.368426
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f22.348630
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c18.705123
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d19.861224
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e19.882225
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f19.657224
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a17.842719
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b16.895619
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e19.515924
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f17.953521
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b17.542920
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c19.957524
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d17.3920
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e19.600724
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c15.876417
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d17.482720
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e18.161221
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f18.729723
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b21.074527
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d17.763321
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e19.763225
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f21.482727
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b21.218627
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c20.803225
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f20.484426
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a19.879224
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b19.461723
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d20.395925
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e23.028530
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b17.310419
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d17.732220
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a16.465918
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d18.781821
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e17.868321
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f16.971119
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a18.554723
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c17.155318
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f18.764923
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b20.465225
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e23.194930
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b20.486424
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c20.499823
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f19.907924
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c17.338119
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d19.664223
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b17.460920
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e18.447421
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f19.71524