ProfileGDS5268 / 1568733_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 55% 57% 55% 57% 57% 57% 59% 58% 55% 61% 57% 62% 62% 50% 64% 67% 62% 67% 62% 63% 53% 55% 56% 59% 60% 57% 64% 59% 54% 56% 59% 55% 54% 58% 54% 55% 58% 52% 52% 58% 52% 57% 51% 58% 55% 57% 56% 54% 49% 54% 52% 50% 48% 51% 50% 54% 52% 61% 48% 49% 56% 61% 53% 61% 55% 53% 46% 50% 50% 54% 54% 57% 51% 51% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a46.438555
GSM386436Untreated HCT116 cells, replicate b50.662457
GSM386437Untreated HCT116 cells, replicate d47.792355
GSM386438Untreated HCT116 cells, replicate e50.789657
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b49.494357
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d48.485257
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e54.018559
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f53.255958
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a46.888755
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b57.405661
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d50.853757
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e61.61262
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a62.51962
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c41.82750
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e66.531964
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f74.029667
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a58.957262
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c73.788267
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e59.457562
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f61.900563
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b44.751553
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c47.873255
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d49.407756
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f54.792459
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b55.432960
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c49.23257
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d60.040464
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f53.469559
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c46.344854
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d50.046856
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e54.11459
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f46.960255
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a46.73254
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b52.638258
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e45.658954
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f48.720655
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b54.299558
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c44.503552
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d43.310452
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e53.415358
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c43.953952
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d51.466857
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e42.919751
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f54.034458
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b49.018355
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d52.50857
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e48.229656
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f46.25854
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b38.585149
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c47.354154
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f41.696552
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a41.261650
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b39.094648
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d42.106951
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e40.189750
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b45.763954
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d44.380852
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a59.806761
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d39.008448
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e38.758749
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f48.898956
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a57.150561
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c45.129353
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f57.819561
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b48.597455
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e44.279553
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b37.533346
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c42.552150
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f40.69850
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c47.848654
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d46.792554
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b52.300757
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e43.383551
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f43.1351