ProfileGDS5268 / 1562751_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 55% 56% 56% 52% 58% 51% 47% 56% 56% 49% 56% 48% 44% 71% 47% 56% 53% 54% 52% 52% 58% 52% 40% 40% 66% 56% 62% 53% 62% 55% 57% 59% 65% 51% 59% 49% 54% 60% 54% 53% 45% 50% 48% 53% 56% 43% 58% 64% 65% 73% 56% 57% 63% 62% 61% 63% 62% 54% 59% 53% 53% 59% 60% 51% 57% 57% 63% 73% 57% 55% 63% 56% 64% 54% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a47.169555
GSM386436Untreated HCT116 cells, replicate b49.56256
GSM386437Untreated HCT116 cells, replicate d49.095756
GSM386438Untreated HCT116 cells, replicate e41.855152
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b51.133858
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d40.098751
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e36.097347
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f48.58956
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a48.439356
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b38.547149
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d48.486756
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e37.99248
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a33.470944
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c87.288571
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e36.897647
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f48.650556
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a43.48953
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c44.270254
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e42.02452
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f42.925952
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b51.77858
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c43.148852
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d29.821740
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f29.825840
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b68.54266
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c47.229256
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d56.897462
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f43.175853
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c60.519362
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d48.478455
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e50.413157
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f53.968559
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a67.758165
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b42.51951
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e54.635759
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f39.518649
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b47.135554
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c58.230660
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d45.805554
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e44.442653
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c35.170445
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d41.06850
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e39.631548
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f44.917853
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b50.703756
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d33.167543
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e52.750758
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f65.354164
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b66.807865
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c91.846173
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f48.344956
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a51.761357
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b62.825263
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d60.608862
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e59.639561
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b64.081363
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d61.849962
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a46.174954
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d55.521559
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e44.146753
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f45.340453
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a54.567159
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c57.69860
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f40.835151
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b52.36657
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e50.791457
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b64.104863
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c91.578573
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f49.907757
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c48.911155
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d62.971163
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b49.790556
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e68.455664
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f47.010754